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US3853804A Expired / Lapsed US ⏱️ 0.0 years remaining

Ionic block elastomeric polymers

Assignee: California Institute of Technology
•
Filing: 1973-07-16
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Granted: 1974-12-10
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Expires: 1993-07-16
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Abstract

Abstract A neutral elastomer is prepared by the urethane linking reaction of diisocyanates with tertiary amino diols. The neutral elastomer is quaternized and is then reacted with an anionic polymer such as heparin to form ionically bonded block elastomeric copolymers. The heparin copolymer has non-thrombogenic characteristics. It can be dissolved in solvents and ultized to form a non-clotting coat on the blood lines in kidney machines.

Inventors

  • 👤 S Yen
  • 👤 A Rembaum

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 19:27
CPC Classifications
C; C08; C08G; C08G18/00; C08G18/06; C08G18/28; C08G18/30; C08G18/32; C08G18/3271; C08G18/329; A; A61; A61L; A61L33/00; A61L33/0005; A61L33/0011; A61L33/0023; C08G18/08; C08G18/0804; C08G18/0809; C08G18/0814; C08G18/10; C08G18/3275; C08L; C08L75/00; C08L75/04

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 11 words
A POLYMERIC SOLUTION CONSISTING ESSENTIALLY OF A POLYMER OF THE FORMULA:
Claim 2
Dependent Claim 11 words
A POLYMERIC SOLUTION CONSISTING ESSENTIALLY OF A POLYMER OF THE FORMULA:
Claim 3
Dependent Claim 57 words
A polymer solution according to claim 1 in which n is 10 to 1,000, A is halo, Z and Y are different members selected from the group consisting of isocyanate, hydroxyl, carboxyl and amino; and R3, R4 and R5 are selected from the group consisting of lower alkyl and hydrogen, and R and R2 are lower alkylene.
Claim 4
Dependent Claim 22 words
A polymer solution according to claim 2 in which Z and Y are selected from isocyanate and hydroxyl and ZY is urethane.
Claim 5
Dependent Claim 18 words
A polymer solution according to claim 1 in which the solvent is a mixture of dimethylformamide and diaminoheptane.
Claim 6
Dependent Claim 22 words
A polymer solution according to claim 2 in which R is ethylene, R2 is methylene and R3, R4 and R5 are methyl.
Claim 7
Independent Claim 22 words
A method of forming a cationic elastomeric polymer comprising the steps of forming a reaction mixture selected from the group consisting of:
Claim 8
Independent Claim 22 words
A method of forming a cationic elastomeric polymer comprising the steps of forming a reaction mixture selected from the group consisting of:
Claim 9
Dependent Claim 16 words
A method according to claim 6 in which said molecular weight is from 1,000 to 3,000.
Claim 10
Dependent Claim 40 words
A method according to claim 7 where R3 and R4 are lower alkyl, Z is isocyanate, Y is hydroxyl, ZY is urethane and R5A is selected from the group consisting of hydrohalic acids, lower alkyl sulfate or lower alkyl halide.
Claim 11
Dependent Claim 39 words
A method according to claim 8 in which said quaternization reaction is conduced in the presence at least a 100 percent stoichiometric excess of the R5A reagent in a common solvent for said intermediate polymer and said cationic polymer.
Claim 12
Dependent Claim 17 words
A method according to claim 6 in which said solvent is a mixture of dimethylformamide and diaminoheptane.

References Cited (Backward Citations)

US3219639A Cited
US3388087A Cited
US3475358A Cited
US3655814A Cited
US3686108A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1977-12-09 1978-06-10 1978-12-10 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1981-12-09 1982-06-10 1982-12-10 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1985-12-09 1986-06-10 1986-12-10 $7700.00 Window Closed / Lapsed

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