Aminoacyloxymethyl esters of penicillins
Abstract
Abstract 1. A PENICILLIN ESTER OF THE FORMULA 2-(R3-N(-R4)-C*(-R2)(-R5)-(CH2)N-COO-CH2-OOC-),3,3- DI(H3C-),6-(R1-CO-NH-)-PENAM IN WHICH FORMULA THE ASTERISK INDICATES THE POSSIBILITY OF AN ASYMMETRIC CARBON ATOM, N INDICATES AN INTEGER FROM 0 TO 1, R1 IS SELECTED FROM THE GROUP CONSISTING OF PHENOXYMETHYL, BENZYL, DIMETHOXYPHENYL, 5-METHYL-3-PHENYL4-ISOXAZOLYL, AND 5-METHYL-3-O-CHLOROPHENYL-4-ISOXAZOLYL; R2 IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, STRAIGHT AND BRANCHED ALKYL WITH FROM 1 TO 4 CARBON ATOMS, METHYLTHIOETHYL, CARBOMETHOXY CARBOMETHOXYMETHYL, PHENYL, BENZYL, AND INDOLYLMETHYLL R3, R4, AND R5 ARE EACH SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, METHYL AND ETHYL, WITH THE PROVISO THAT R4 AND R5 TOGETHER WITH THE NITROGEN AND CARBON ATOM BETWEEN THEM CAN FORM PART OF A TETRAHYDROPYRROLE RING, AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF.
Inventors
- 👤 V Godtfredsen
- 👤 S Rachlin
- 👤 Daehne W Von
- 👤 E Frederiksen
Bibliographic Details
Claims Analysis
Total Claims: 2References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1977-11-25 | 1978-05-27 | 1978-11-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1981-11-25 | 1982-05-27 | 1982-11-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1985-11-25 | 1986-05-27 | 1986-11-26 | $7700.00 | Window Closed / Lapsed |