Novel process for producing antibiotics bleomycin
Abstract
Abstract GROUP AND AT LEAST ONE BASIC GROUP SELECTED FROM AMINO, IMINO, GUANIDINO, AMIDINO AND SULFONIUM GROUPS AND NITROGEN-CONTAINING CYCLIC COMPOUNDS, OR IN THE PRESENCE OF A COMPOUND CONVERTIBLE IN THE CULTURE LIQUOR TO SUCH AMINO COMPOUND AS MENTIONED ABOVE, THEREBY SELECTIVELY PRODUCING A KNOWN OR NOVEL BLEOMYCIN COMPONENT CORRESPONDING TO THE SAID AMINO COMPOUND OR TO AN AMINO COMPOUND DERIVED FROM THE ABOVE-MENTIONED COMPOUND, AND THEN THE KNOWN OR NOVEL BLEOMYCIN IS RECOVERED BY KNOWN MEANS FROM THE CULTURE MEDIUM. A novel process for producing antibiotics bleomycins by innoculating and aerobically culturing in a nutrient sourcecontaining medium a bleomycin-producing strain belonging to the actinomyces, wherein the culture is effected in the presence of an amino compound having at least one
Inventors
- 👤 H Umezawa
- 👤 K Maeda
- 👤 A Fujii
- 👤 N Shimada
- 👤 T Takita
- 👤 Y Nakayama
- 👤 H Chimura
Bibliographic Details
Claims Analysis
Total Claims: 2References Cited (Backward Citations)
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