N-(3,4-dihydro naphthyl)-n'phenyl piperazines

Abstract

Abstract 1. A DIHYDRONAPHTHALENE COMPOUND HAVING THE FORMULA (B)K<(-C(-R2)=C(-N<(-(CH2)N-N(-R3)-(CH2)2-))-(A)J-(R,R1- 1,2-PHENYLENE)-) WHEREIN R AND R1 ARE EACH INDIVIDUALLY SELECTED FROM THE GROUP CONSISTING OF HYDROGE, HALOGEN, (LOWER)ALKYL, (LOWER)ALKOXY, NITRO, 8LOWER)ALKYL THIO OR 8LOWER)ALKYL SULFONYL WITH THE PROVISO THAT ONE OF R AND R1 IS HYDROGEN; R2 IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, PHENYL OR CARBOXYL; R3 IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, 8LOWER)ALKYL, PHENYL, PHENYL SUBSTITUTED WITH A HALOGEN, TRIFLUOROMETHYL, (LOWER)ALKOXY OR (LOWER) ALKYL, PICOLYL, BENZYL, BENZYL SUBSTITUTED WITH A HALOGEN, (LOWER)ALKOXY OR (LOWER)ALKYL, (LOWER)ALKOXY CARBONYL, N-MONOALKYL ACETAMIDE, N,N-DIALKYL ACETAMIDE, N-PHENYL ACETAMIDE, N-MONOALKYL PROPIONAMIDE OR N,N-DIALKYLPROPIONAMIDE, N IS A WHOLE INTEGER OF 2 OR 3, A AND B ARE EACH INDEPENDENTLY SELECTED FROM THE RADICALS -CH2-CH2-OR -CH(CH3)-CH2-; J IS L AND K IS 0; AND THE (LOWER)ALKYL AND ALKYL PORTIONS OF THE GROUPS HAVE 1 TO 6 CARBON ATOMS; OR A PHARMACEUTICALLY ACCEPATBLE ACID ADDITION SALT THEREOF.

Inventors

• 👤 G Perri
• 👤 M Mastursi
• 👤 S Lembo
• 👤 R Viterbo

Bibliographic Details