Patent US3830106A successfully refreshed from Google Patents.
US3830106A
Expired / Lapsed
US
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Sampling device
Assignee: Glaxo Laboratories Ltd
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Filing: 1973-02-26
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Granted: 1974-08-20
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Expires: 1993-02-26
Abstract
Abstract A sampling device is described for removing dialysable fluids from a liquid for analysis. The device comprises a tubular dialysis membrane fixed on an elongated support, a helical passage being provided between the membrane and the support. In use, a carrier fluid is passed through the helical passage to remove for analysis fluids which pass through the membrane from a liquid in which the device is placed. The device is useful for monitoring chemical reactions, particularly fermentations.
Inventors
- 👤 W Gardiner
- 👤 K Briggs
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 20:42
CPC Classifications
G; G01; G01N; G01N1/00; G01N1/02; G01N1/10; B; B01; B01D; B01D61/00; B01D61/24; B01D61/28; G01N1/22; G01N2001/2285; G01N1/28; G01N1/38; G01N2001/381; G01N2001/383
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
123 words
A sampling device for removing dialysable materials from a liquid for analysis, said device comprising a cylindrical member having a helical groove formed in its exterior cylindrical surface, means fixing a tubular dialysis membrane over the said member whereby the groove and the membrane together form a helical passage for a carrier fluid, and inlet and outlet passages extending into said cylindrical member from the same end thereof, respectively communicating with opposite ends of said helical passage and through which a carrier fluid can be introduced to and withdrawn from the said helical passage, said membrane defining the outermost surface of said device whereby said device may be extended into and exposed to a body of a reacting medium without withdrawing samples therefrom.
Claim 2
Dependent Claim
123 words
A sampling device for removing dialysable materials from a liquid for analysis, said device comprising a cylindrical member having a helical groove formed in its exterior cylindrical surface, means fixing a tubular dialysis membrane over the said member whereby the groove and the membrane together form a helical passage for a carrier fluid, and inlet and outlet passages extending into said cylindrical member from the same end thereof, respectively communicating with opposite ends of said helical passage and through which a carrier fluid can be introduced to and withdrawn from the said helical passage, said membrane defining the outermost surface of said device whereby said device may be extended into and exposed to a body of a reacting medium without withdrawing samples therefrom.
Claim 3
Dependent Claim
15 words
A device as claimed in claim 1 wherein the helical groove is of V-shaped cross-section.
Claim 4
Dependent Claim
16 words
A device as claimed in claim 1 wherein the cylindrical member is formed of synthetic plastic.
Claim 5
Dependent Claim
16 words
A device as claimed in claim 3 wherein the synthetic plastic is a polyamide or polytetrafluoroethylene.
Claim 6
Dependent Claim
25 words
A device as claimed in claim 1 wherein the fixing means are ring seals located adjacent but outwardly of the ends of the helical groove.
Claim 7
Dependent Claim
12 words
A device as claimed in claim 1 wherein said membrane is tubular.
Claim 8
Dependent Claim
17 words
A device as claimed in claim 6 wherein the membrane is one of cellulosic or polytetrafluoroethylene material.
Claim 9
Independent Claim
59 words
A method of removing dialysable materials from a liquid for analysis, comprising the steps of: passing a carrier fluid for said materials through a helical passage having a portion defined by a dialysis membrane, extending said passage into said liquid and introducing and withdrawing said carrier fluid to and from said passage from positions adjacent the same end thereof.
Claim 10
Independent Claim
59 words
A method of removing dialysable materials from a liquid for analysis, comprising the steps of: passing a carrier fluid for said materials through a helical passage having a portion defined by a dialysis membrane, extending said passage into said liquid and introducing and withdrawing said carrier fluid to and from said passage from positions adjacent the same end thereof.
Claim 11
Dependent Claim
36 words
A method as claimed in claim 8 wherein the liquid is a fermentation broth and a sterile carrier liquid is passed through the device to remove dialysable liquids from the broth through a hydrophilic dialysis membrane.
Claim 12
Dependent Claim
16 words
A method as claimed in claim 9 wherein the fermentation broth is a penicillin fermentation broth.
References Cited (Backward Citations)
US3494470A
Cited
US3483990A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1977-08-19 | 1978-02-18 | 1978-08-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1981-08-19 | 1982-02-18 | 1982-08-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1985-08-19 | 1986-02-18 | 1986-08-20 | $7700.00 | Window Closed / Lapsed |