Method and apparatus for renal dialysis monitoring
Abstract
Abstract THE APPLICATION DISCLOSES METHOD AND APPARATUS FOR MONITORING THE PROGRESS OF RENTAL DIALYSIS, I.E., REMOVAL OF IMPURITIES FROM THE BLOODSTREAM. A RADIOACITIVELY LABELLED GLOMERULAR SUBSTANCE IS INJECTED INTO THE BLOODSTREAM. THE RADIOACTIVE SUBSTANCE IS DIALYZED FROM THE BLOODSTREAM AT SUBSTANTIALLY THE SAME RATE AS THE IMPURITIES. THE EXACT RELATIONSHIP BETWEEN THE RATES OF REMOVAL OF IMPURITIES AND OF THE RADIOACTIVE SUBSTANCE IS DETERMINED EXPERIMENTALLY. A DETECTOR IS ARRANGED TO MONITOR THE AMOUNT OF RADIOACTIVE MATERIAL REMAINING IN THE BLOODSTREAM AND TO PRESENT A CONTINUOUS READOUT SHOWING THE FRACTION OF THE INITIAL RADIOACTIVELY LABELLED SUBSTANCE (AND THEREBY THE FRACTION OF IMPURITIES) REMAINING IN THE BLOOD STREAM. THE DETECTION METER IS INITIALLY CALIBRATED TO READ 100% AT THE START OF THE DIALYSIS PROCEDURE; DIALYSIS IS CONTINUED UNTIL A SUITABLE READING SUCH AS 30% (MEANING THE LEVEL OF REMAINING RADIOACTIVE SUBSTANCE IS 30% OF THE ORIGINAL LEVEL) IS REACHED. A TYPICAL RADIOACTIVE ISOTOPE MATERIAL SUITABLE FOR USE AS A LABELLING MATERIAL IN113M OR TC99M; A SUITABLE GLOMERULAR SUBSTANCE SUITABLE FOR USE AS A CARRIER IS DTPA(DIETHYLTRIAMINEPENTAACETIC ACID).
Inventors
- 👤 J Waters
Bibliographic Details
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