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US3821081A Expired / Lapsed US ⏱️ 0.0 years remaining

Process for producing 7-amino desacetoxy cephalosporanic acid

Assignee: Toyo Jozo KK
•
Filing: 1972-03-15
•
Granted: 1974-06-28
•
Expires: 1992-03-15
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Abstract

Abstract D R A W I N G 7-Amino desacetoxy cephalosporanic acid represented by the general formula, IS PRODUCED ACCORDING TO A PROCESS IN WHICH AN ALKALI METAL SALT OF A 7-ACYLAMINO DESACETOXY CEPHALOSPORANIC ACID REPRESENTED BY THE GENERAL FORMULA, WHEREIN R is a benzyl or phenoxymethyl group, and M is an alkali metal atom capable of forming a water-soluble salt, is treated with a carrier containing culture filtrate of an enzyme-producing strain belonging to the genus Bacillus which can decompose the amide bond of the said compound, said strain being Bacillus megaterium B-400 FERM-P No. 748, or is treated in an aqueous medium with an enzyme preparation containing said enzymeproducing strain.

Inventors

  • 👤 J Abe
  • 👤 K Matsumoto
  • 👤 T Fujii
  • 👤 T Watanabe
  • 👤 T Yamaguchi

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-04 07:52
CPC Classifications
C; C12; C12N; C12N9/00; C12N9/14; C12N9/78; C12N9/80; C12P; C12P35/00; C12P35/02; Y; Y10; Y10S; Y10S435/00; Y10S435/814; Y10S435/815; Y10S435/8215; Y10S435/822; Y10S435/832; Y10S435/837

Claims Analysis

Total Claims: 3
Claim 1
Independent Claim 19 words
A process according to claim 1, wherein said deacylating enzyme is adsorbed on said carrier from a culture filtrate.
Claim 2
Dependent Claim 70 words
A process according to claim 1, wherein said 7-acylamino desacetoxy cephalosporanic acid is in the form of a water-soluble sodium or potassium salt at a concentration within the range of from 0.1 to 20 mg/ml and the salt is treated at a pH within the range of about 7 to 8 at a reaction temperature from 30* to 45* C. for a period of from about 5 to 30 hours.
Claim 3
Dependent Claim 32 words
A process according to claim 1, wherein said carrier is an inorganic carrier selected from the group consisting of Celite, terra alba, active clay, kaolin, active carbon, silica gel, and cation exchanger.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1977-06-27 1977-12-27 1978-06-28 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1981-06-27 1981-12-27 1982-06-28 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1985-06-27 1985-12-27 1986-06-28 $7700.00 Window Closed / Lapsed

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