Butyramidine
Abstract
Abstract NEW DERIVATIVES AND ANALOGUES OF BUTYRAMIDINE HAVING THE GENERAL FORMULA: A-O-CH2-CH(-OH)-CH2-C(=N-R1)-N(-R2)-R3 IN WHICH A REPRESENTS A-NAPHTHYL OR B-NAPHTHYL, R3 REPRESENTS A HYDROGEN ATOM OR A LOWER ALKYL GROUP HAVING 1 TO 3 CARBON ATOMS, R2 REPRESENTS A HYDROGEN ATOM, A HYDROXYL GROUP OR A LOWER ALKYL GROUP HAVING 1 TO 3 CARBON ATOMS, AND R1 REPRESENTS A HYDROGEN ATOM, R1 AND R2 CONSIDERED TOGETHER BEING CAPABLE OF FORMING WITH THE TWO NITROGEN ATOMS AND THE CARBON ATOM OF THE AMIDINE FUNCTION OF 2-IMIDAZOLINYL OR 1,4,5,6-TETRAHYDRO-2-PYRIMIDINYL RADICAL WHEN R3 IS A HYDROGEN ATOM. THE COMPOUNDS OF FORMULA I AND THE NON-TOXIC ACID ADDITION SALTS THEREOF ARE ACTIVE B-BLOCKING AGENTS AND ARE USED IN THE TREATMENT OF CARDIAC TROUBLES.
Inventors
- 👤 V Lafon
Bibliographic Details
Claims Analysis
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