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US3809782A Expired / Lapsed US ⏱️ 0.0 years remaining

Tubocurarine antigens and antibodies specific therefor

Assignee: F Hoffmann La Roche AG
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Filing: 1972-03-10
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Granted: 1974-05-07
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Expires: 1992-03-10
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Abstract

Abstract Antigens are prepared by coupling tubocurarine derivatives to immunogenic carrier materials. The coupling is effected via a linking group derived from an amino acid involving an azo link to the tubocurare moiety and an amide linkage to the immunogenic carrier material. In preferred embodiments, proteins are used as the carrier materials. The resulting antigens produce immunological effects when injected into host animals, including the formation of antibodies specific for tubocurarine components in biological fluids.

Inventors

  • 👤 S Spector

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 00:52
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/531; C; C07; C07K; C07K16/00; C07K16/16; G01N33/536; G01N33/537; G01N33/539; Y; Y10; Y10S; Y10S436/00; Y10S436/815; Y10S436/823; Y10S530/00; Y10S530/806

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 13 words
The antigen of claim 1 wherein said linking group is a p-azo-benzoyl group.
Claim 2
Dependent Claim 14 words
The antigen of claim 1 wherein said tubocurarine derivative is of the d-enantiomeric series.
Claim 3
Dependent Claim 12 words
The antigen of claim 3 wherein said tubocurarine derivative is d-tubocurarine chloride.
Claim 4
Dependent Claim 13 words
The antigen of claim 1 wherein said immunogenic carrier material is a protein.
Claim 5
Dependent Claim 12 words
The antigen of claim 5 wherein said protein is bovine serum albumin.

References Cited (Backward Citations)

US2388260A Cited
US2957808A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1977-05-06 1977-11-05 1978-05-07 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1981-05-06 1981-11-05 1982-05-07 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1985-05-06 1985-11-05 1986-05-07 $7700.00 Window Closed / Lapsed

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