2-phenylimino-imidazolidines,their 2-aniline-2-imidazoline tautomers and salts thereof
Abstract
Abstract COMPOUNDS OF THE FORMULA 1-R3,2-((R1,R2-PHENYL)-N=),3-R4-IMIDAZOLIDINE WHEREIN R1 AND R2, WHICH MAY BE INDENTICAL TO OR DIFFERENT FROM EACH OTHER, ARE EACH HYDROGEN, CHLORINE, BROMINE, TRIFLUOROMETHYL, CYANO, METHOXY, METHYL OR ETHYL, AND R3 AND R4, WHICH MAY BE IDENTICAL TO OR DIFFERENT FROM EACH OTHER, ARE EACH HYDROGEN, ALKYL OR 1 TO 3 CARBON ATOMS, CYCLOALKYL OF 5 TO 7 CARBON ATOMS OR ALKENYL OF 3 TO 5 CARBON ATOMS, PROVIDED, HOWEVER, THAT R3 AND R4 ARE OTHER THAN BOTH HYDROGEN AT THE SAME TIME, THEIR TAUTOMERS OF THE FORMULA 1-R3,2-((R1,R2-PHENYL)-NH-)-2-IMIDAZOLINE WHEREIN R1 AND R2 HAVE THE MEANINGS DEFINED ABOVE, AND R3 HAS THE MEANINGS DEFINED ABOVE EXCEPT HYDROGEN, AND NON-TOXIC, PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF; THE COMPOUNDS AS WELL AS THIER SALTS ARE USEFUL AS HYPOTENSIVES.
Inventors
- 👤 W Kummer
- 👤 W Hoefke
- 👤 H Staehle
- 👤 H Koeppe
Bibliographic Details
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