US3804533A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Rotor for fluorometric measurements in fast analyzer of rotary
Assignee: United States Atomic Energy Commission
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Filing: 1972-11-29
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Granted: 1974-04-16
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Expires: 1992-11-29
Abstract
Abstract An improved rotor is provided for simultaneously making fluorometric measurements on a multiplicity of discrete samples. A multiplicity of sample analysis chambers or cuvettes are arranged side by side in a circular array to form a rotary cuvette system within the rotor. Each chamber comprises an inclined, open-ended cavity adapted to retain liquids within its radial extremity upon rotation. Surface fluorescence measurements are made while sample liquids are so retained by means of a fluorescence excitation light source and photodetector adapted, respectively, to direct a light beam and detect fluorescence emitted through the open end of the sample analysis chamber. Sample and reagent loading cavities, adapted to be loaded under static conditions, discharge upon rotation through liquid mixing and transfer passageways into respective sample analysis chambers.
Inventors
- 👤 C Scott
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 09:52
CPC Classifications
G; G01; G01N; G01N21/00; G01N21/01; G01N21/03; G01N21/07
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
113 words
An improved rotor for simultaneously making surface fluorescence measurements of a multiplicity of samples comprising a generally disk-shaped member having a top surface, said diskshaped member defining: a. a circular array of sample analysis cuvettes for respectively receiving liquid samples and reagents; said cuvettes each comprising an elongated, radially extending cavity having an open end in said top surface and a closed end disposed radially outward from said open end for retaining preselected amounts of liquid samples and reagents during rotation, said closed end and sample and reagent liquid retained therein being visible through said open end during rotation; and b. means for loading sample and reagent liquids into said sample analysis cuvettes.
Claim 2
Dependent Claim
113 words
An improved rotor for simultaneously making surface fluorescence measurements of a multiplicity of samples comprising a generally disk-shaped member having a top surface, said diskshaped member defining: a. a circular array of sample analysis cuvettes for respectively receiving liquid samples and reagents; said cuvettes each comprising an elongated, radially extending cavity having an open end in said top surface and a closed end disposed radially outward from said open end for retaining preselected amounts of liquid samples and reagents during rotation, said closed end and sample and reagent liquid retained therein being visible through said open end during rotation; and b. means for loading sample and reagent liquids into said sample analysis cuvettes.
Claim 3
Dependent Claim
33 words
The improved rotor of claim 1 wherein said radially extending cavity comprises a generally cylindrical cavity termiNating in a hemispherical closed-end portion, said cylindrical cavity being inclined with respect to said top surface.
Claim 4
Dependent Claim
38 words
The improved rotor of claim 1 wherein said closed end of said radially extending cavity terminates in a cylindrical surface having a radius equal to the displacement of said surface from the center of rotation of said rotor.
Claim 5
Dependent Claim
106 words
The improved rotor of claim 1 wherein said means for loading sample and reagent liquids into said sample analysis cuvettes comprises a circular array of sample and reagent loading cavities having open ends in said top surface and being disposed radially inward from said array of sample analysis cuvettes; one pair of said sample and reagent loading cavities being provided for each of said cuvettes; and passageways communicating between each of said pairs of sample and reagent loading cavities and respective cuvettes in said array of sample analysis cuvettes to effect transfer of liquids from said sample and reagent loading cavities to said cuvettes upon rotation.
Claim 6
Dependent Claim
29 words
The improved rotor of claim 4 wherein said sample and reagent loading cavities are generally cylindrical in shape and are inclined downwardly from said top surface and radially outward.
Claim 7
Dependent Claim
33 words
The improved rotor of claim 5 wherein said passageways communicating between each of said pairs of sample and reagent loading cavities and respective cuvettes intersect said cavities at their lower, radially outer ends.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1977-04-15 | 1977-10-15 | 1978-04-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1981-04-15 | 1981-10-15 | 1982-04-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1985-04-15 | 1985-10-15 | 1986-04-16 | $7700.00 | Window Closed / Lapsed |