US3555284A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Multistation, single channel analytical photometer and method of use
Assignee: Individual
•
Filing: 1968-12-18
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Granted: 1971-01-12
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Expires: 1988-12-18
Abstract
Abstract An analytical photometer is provided for simultaneously determining the presence of a common substance in a multiplicity of discrete samples. A multiplicity of sample chambers with axially aligned transparent windows are arranged within a centrifuge rotor to provide a rotary cuvette system. Solution handling systems comprising sets of interconnected, solutionaccepting chambers are disposed generally in radial alignment with the sample chambers forming the cuvette system. The solution-accepting chambers of the solution handling systems are shaped and sized to retain liquid when the rotor is at rest, and to release the liquid to the cuvettes when the rotor is spinning. A single light source and a photodetecting unit are aligned with the windows to determine chemical species concentrations by light absorbancy in the samples contained in the cuvettes. Means for receiving the output from the photodetecting unit are provided for individually indicating the phototransmittance of the samples within each cuvette.
Inventors
- 👤 Norman G Anderson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 19:40
CPC Classifications
G; G01; G01N; G01N21/00; G01N21/01; G01N21/03; G01N21/07; B; B04; B04B; B04B5/00; B04B5/04; B04B5/0407; Y; Y10; Y10T; Y10T436/00; Y10T436/11; Y10T436/111666
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
186 words
A photometric solution analyzer for the simultaneous determination of a common substance in a multiplicity of discrete samples comprising: a. a power-driven rotor assembly defining; 1. a multiplicity of sample analysis chambers for accepting liquid samples to be analyzed, said rotor assembly having transparent walls adjacent said sample analysis chambers for permitting the passage of light therethrough, and 2. a multiplicity of chambers adapted to retain liquid samples and reactants when said rotor assembly is at rest, and to release said liquid samples and reactants to said sample analysis chambers when said rotor is rotated; b. a light source for providing a beam of light incident on said rotor assembly at a point corresponding to the radial position of said sample analysis chambers; c. means for detecting light from said light source after it has passed through said sample analysis chambers, said means for detecting light generating an output signal proportional to the intensity of light detected; and d. means receiving the output from said light detecting means for continuously and simultaneously indicating the presence of said common substance within each of said sample analysis chambers.
Claim 2
Dependent Claim
186 words
A photometric solution analyzer for the simultaneous determination of a common substance in a multiplicity of discrete samples comprising: a. a power-driven rotor assembly defining; 1. a multiplicity of sample analysis chambers for accepting liquid samples to be analyzed, said rotor assembly having transparent walls adjacent said sample analysis chambers for permitting the passage of light therethrough, and 2. a multiplicity of chambers adapted to retain liquid samples and reactants when said rotor assembly is at rest, and to release said liquid samples and reactants to said sample analysis chambers when said rotor is rotated; b. a light source for providing a beam of light incident on said rotor assembly at a point corresponding to the radial position of said sample analysis chambers; c. means for detecting light from said light source after it has passed through said sample analysis chambers, said means for detecting light generating an output signal proportional to the intensity of light detected; and d. means receiving the output from said light detecting means for continuously and simultaneously indicating the presence of said common substance within each of said sample analysis chambers.
Claim 3
Dependent Claim
127 words
a multiplicity of chambers adapted to retain liquid samples and reactants when said rotor assembly is at rest, and to release said liquid samples and reactants to said sample analysis chambers when said rotor is rotated; b. a light source for providing a beam of light incident on said rotor assembly at a point corresponding to the radial position of said sample analysis chambers; c. means for detecting light from said light source after it has passed through said sample analysis chambers, said means for detecting light generating an output signal proportional to the intensity of light detected; and d. means receiving the output from said light detecting means for continuously and simultaneously indicating the presence of said common substance within each of said sample analysis chambers.
Claim 4
Dependent Claim
127 words
a multiplicity of chambers adapted to retain liquid samples and reactants when said rotor assembly is at rest, and to release said liquid samples and reactants to said sample analysis chambers when said rotor is rotated; b. a light source for providing a beam of light incident on said rotor assembly at a point corresponding to the radial position of said sample analysis chambers; c. means for detecting light from said light source after it has passed through said sample analysis chambers, said means for detecting light generating an output signal proportional to the intensity of light detected; and d. means receiving the output from said light detecting means for continuously and simultaneously indicating the presence of said common substance within each of said sample analysis chambers.
Claim 5
Dependent Claim
33 words
The photometric analyzer of claim 1 wherein said sample analysis chambers comprise a multiplicity of radially oriented elongated cavities disposed in a circular array about the center of rotation of said rotor assembly.
Claim 6
Dependent Claim
23 words
The photometric analyzer of claim 2 wherein said sample analysis chambers are fabricated by sandwiching a slotted ring between layers of transparent material.
Claim 7
Dependent Claim
24 words
The photometric analyzer of claim 3 wherein said slotted ring is fabricated of polytetrAfluorethylene and said layers of transparent material are fabricated of glass.
Claim 8
Dependent Claim
53 words
The photometric analyzer of claim 1 wherein said chambers adapted to retain liquid samples and reactants when said rotor assembly is at rest are disposed in a circular array in radial alignment with and spaced radially inward from said sample analysis chambers with respect to the center of rotation of said rotor assembly.
Claim 9
Dependent Claim
16 words
The photometric analyzer of claim 1 wherein said means for detecting light comprises a photomultiplier tube.
Claim 10
Dependent Claim
30 words
The photometric analyzer of claim 1 wherein said means for continuously and simultaneously indicating the presence of said common substance within each of said sample analysis chambers comprises an oscilloscope.
Claim 11
Independent Claim
127 words
A method for photometrically analyzing a multiplicity of discrete samples to simultaneously determine the presence of a single substance therein, comprising: a. introducing preselected volumes of liquids necessary to produce photometrically measurable solutions into a first series of chambers within a rotor assembly while said rotor assembly is at rest; b. rotating said rotor assembly at a speed wherein centrifugal force causes said volumes of liquids to be transferred to a second series of chambers located radially from the center of rotation of said rotor system a greater distance than said first series of chambers; and c. continuously and simultaneously scanning the phototransmittance of the contents of said second series of chambers while said rotor is rotating to determine the concentration of a preselected substance contained therein.
Claim 12
Independent Claim
127 words
A method for photometrically analyzing a multiplicity of discrete samples to simultaneously determine the presence of a single substance therein, comprising: a. introducing preselected volumes of liquids necessary to produce photometrically measurable solutions into a first series of chambers within a rotor assembly while said rotor assembly is at rest; b. rotating said rotor assembly at a speed wherein centrifugal force causes said volumes of liquids to be transferred to a second series of chambers located radially from the center of rotation of said rotor system a greater distance than said first series of chambers; and c. continuously and simultaneously scanning the phototransmittance of the contents of said second series of chambers while said rotor is rotating to determine the concentration of a preselected substance contained therein.
Claim 13
Dependent Claim
34 words
The method of claim 8 wherein following the introduction of liquids into said first series of chambers, the rotor is accelerated, decelerated, and then reaccelerated to facilitate mixing within said second series of chambers.
Claim 14
Dependent Claim
87 words
The method of claim 8 wherein following the rotation of said rotor assembly at a speed causing transfer of said volumes of liquid from said first series of chambers to said second series of chambers, said rotor assembly is brought to rest and said first series of chambers replaced with a third series of chambers containing further preselected volumes of liquids, and wherein said rotor assembly is again rotated to effect the transfer of liquids from said third series of chambers to said second series of chambers.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1974-01-11 | 1974-07-13 | 1975-01-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1978-01-11 | 1978-07-13 | 1979-01-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1982-01-11 | 1982-07-13 | 1983-01-12 | $7700.00 | Window Closed / Lapsed |