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US3791222A Expired / Lapsed US ⏱️ 0.0 years remaining

Dissolution testing device

Assignee: Warner Lambert Co LLC
•
Filing: 1972-04-07
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Granted: 1974-02-12
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Expires: 1992-04-07
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Abstract

Abstract The specific disclosure provides a dissolution rate testing device for tablets and capsules comprising a closed chamber having a solution medium therein, a removable holder positioned in the bottom of the chamber for at least one tablet or capsule, and an impeller for circulating the solution medium about the at least one tablet or capsule so that the dissolution rate can be observed.

Inventors

  • 👤 F Goodhart
  • 👤 W Campbell

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-04 12:18
CPC Classifications
B; B01; B01F; B01F21/00; B01F21/10; B01F21/20; B01F35/00; B01F35/20; G; G01; G01N; G01N13/00; B01F2101/00; B01F2101/23; G01N2013/006; G01N35/00; G01N2035/00178; G01N2035/00188; G01N2035/00198; G01N33/00; G01N33/15

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 132 words
A device for determining dissolution rates of tablets or capsules comprising, in combination: a closed container for a solution medium, a passageway about the periphery of said container through which a fluid flows, means connected to said passageway for controlling the temperature of said fluid, a removable holder positioned within and at the bottom of said container, said holder comprising a centrally located upwardly extending elongated member for manually removing said holder from said container, and having at least one hole in the upper side thereof for said at least one tablet or capsule, a shaft extending vertically through the top of said container, an impeller at the lower end of said shaft for agitating said solution medium above said holder, and motive means operatively connected to the top of said shaft.
Claim 2
Independent Claim 132 words
A device for determining dissolution rates of tablets or capsules comprising, in combination: a closed container for a solution medium, a passageway about the periphery of said container through which a fluid flows, means connected to said passageway for controlling the temperature of said fluid, a removable holder positioned within and at the bottom of said container, said holder comprising a centrally located upwardly extending elongated member for manually removing said holder from said container, and having at least one hole in the upper side thereof for said at least one tablet or capsule, a shaft extending vertically through the top of said container, an impeller at the lower end of said shaft for agitating said solution medium above said holder, and motive means operatively connected to the top of said shaft.
Claim 3
Dependent Claim 13 words
The device of claim 1, further comprising means for sampling said solution medium.
Claim 4
Dependent Claim 22 words
The device of claim 2 wherein said sampling means comprises conduit means for removing a sample of said solution at predetermined intervals.
Claim 5
Dependent Claim 20 words
The device of claim 2 wherein said sampling means comprises means for continuously sampling said solution at a predetermined rate.
Claim 6
Dependent Claim 34 words
The device of claim 4 further comprising means operatively connected to said sampling means for generating a signal representative of the amount of an active ingredient in said at least one tablet or capsule.
Claim 7
Dependent Claim 32 words
The device of claim 4 further comprising means operatively connected to said sampling means for generating a display representative of the rate of dissolution of said at least one tablet or capsule.
Claim 8
Dependent Claim 26 words
The device of claim 1 wherein said holder comprises a plurality of holes in the upper side thereof, said holes being spaced from said elongated member.

References Cited (Backward Citations)

US3192774A Cited
US3223486A Cited
US3545864A Cited
US3618395A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1977-02-11 1977-08-13 1978-02-12 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1981-02-11 1981-08-13 1982-02-12 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1985-02-11 1985-08-13 1986-02-12 $7700.00 Window Closed / Lapsed

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