1,2,3,6-tetrahydro-4-pyridylmethyl carboxylates

Abstract

Abstract RACEMIC MIXTURES OF COMPOUNDS OF THE FORMULA 1-R1,4-(R2-COO-CH2-)-1,2,3,6-TETRAHYDROPYRIDINE WHEREIN R1 IS HYDROGEN, ALKYL OF 1 TO 8 CARBON ATOMS, CHLORO(ALKYL OF 1 TO 8 CARBON ATOMS), CYANO-(ALKYL OF 1 TO 8 CARBON ATOMS), HYDROXY-(ALKYL OF 1 TO 8 CARBON ATOMS), PHENYL-(ALKYL OF 1 TO 8 CARBON ATOMS), ALKENYL OF 3 TO 4 CARBON ATOMS OR ALKINYL OF 3 TO 4 CARBON ATOMS, AND R2 IS -C(-R3)(-R4)-C6H5, -CH(-R5)-R6, FLUOREN-9-YL OR XANTHEN-9-YL WHERE R3 IS HYDROXYL OR, TOGETHER WITH R4 AND THE CARBON ATOM TO WHICH THEY ARE ATTACHED, A 5- TO 6-MEMBERED SATURATED CARBOXYLIC RING, R4 AND R5 ARE EACH ALKYL OF 1 TO 4 CARBON ATOMS, CYCLOALKYL OF 5 TO 6 CARBON ATOMS OR PHENYL, AND R6 IS CYCLOALKYL OF 5 TO 6 CARBON ATOMS OR PHENYL, OPTICALLY ACTIVE ANTIPODES THEREOF, QUARTERNARY AMMONIUM SALTS THEROF, AND NON-TOXIC ACID ADDITION SALTS OF SAID RACEMATES AND OPTICALLY ACTIVE ANTIPODES; THE COMPOUNDS ARE USEFUL AS ANTICHOLINGERICS.

Inventors

• 👤 G Walther
• 👤 R Bauer
• 👤 H Hubner
• 👤 R Banholzer

Bibliographic Details