Tasteless methenamine mandelate
Abstract
Abstract A SUBSTANTIALLY TASTELESS METHENAMINE MANDELATE SUSPENSION CONTAINS PARTICLES OF METHENAMINE MANDELATE ENVELOPED IN A COATING OF ETHYL CELLULOSE AND AT LEAST ONE SECONDARY COATING INGREDIENT INCLUDING HYDROGENATED CASTOR OIL, PARAFFIN, AND/OR A POLYETHYLENE GLYCOL POLYMER OR MIXTURE OF POLYETHYLENE GLYCOL POLYMERS. THE COATING IS APPLIED FROM A SOLVENT SOLUTION, USING CONVENTIONAL SPRAY DRYING TECHNIQUES. THE COATED METHENAMINE MANDELATE PARTICLES ARE SUSPENDED IN A VEGETABLE OIL VEHICLE TO WHICH A SUSPENSION STABILIZER MAY BE ADDED. THIS SUSPENSION IS STABLE, PALATABLE AND THERAPEUTICALLY ACTIVE, UPON ORAL ADMINISTRATION, FOR THE TREATMENT OF URINARY INFECTIONS. THE ADDITION OF ARTIFICIAL SWEETENERS TO MASK THE NORMALLY UNPLEASANT TASTE OF METHENAMINE MANDELATE IS NOT REQUIRED. FLAVOR, COLORING AND RELATIVELY SMALL AMOUNTS OF SUGAR MAY BE ADDED TO THE SUSPENSION TO PROVIDE SPECIFIC TASTE QUALITIES, IF DESIRED.
Inventors
- 👤 F Goodhart
- 👤 J Draper
Bibliographic Details
Claims Analysis
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| 3.5 Years (Year 4) | 1976-12-17 | 1977-06-18 | 1977-12-18 | $2000.00 | Window Closed / Lapsed |
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