(benzimidazol-2-ylthio)-benzoyl-alkyl carboxylic acids and their alkyl esters
Abstract
Abstract WHEREIN THIAZOLO(3,2-A)BENZIMIDAZOLE 2-(R2-OOC-(CH2)N-),3-HO,3-(R3-C6H4-),R1-2,3-DIHYDRO- 2-(R3-C6H4-CO-CH(-(CH2)N-COO-R2)-S-),R1-BENZIMIDAZOLE, OR R1 IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, HALOGEN, (LOWER)ALKYL, TRIFLUOROMETHYL, NITRO AND AMINO; R2 IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN AND (LOWER)ALKYL; R3 IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, HALOGERN, (LOWER)ALKYL, TRIFLUOROMETHYL, NITRO, AMINO, PHENYL, HALOPENYL AND (LOWER)ALKYLPHENYL; N IS AN INTEGER OF FROM 1 TO ABOUT 3; AND THE PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF. NOVEL COMPOUNDS OF FORMULA I AND FORMULA II HAVE BEEN PREPARED WHICH HAVE CNS DEPRESSANT AND ANTITUBERCULAR ACTIVITY:
Inventors
- 👤 P Wei
- 👤 S Bell
Bibliographic Details
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