2-imidazol-1-yl benzophenones
Abstract
Abstract 2-IMIDAZOL-1-YL BENZOPHENONES OF THE FORMULA II 1-(2-((CH3)2-N-CH(-R6)-),4-R1,5-R0-IMIDAZOL-1-YL),2-((R2, R3-PHENYL)-CO-),R4,R5-BENZENE WHEREIN R0 AND R1 ARE SELECTED FROM THE GROUP CONSISTING OF HYDROGEN AND ALKYL OF 1 TO 3 CARBON ATOMS, AND HYDROXYMETHYL; WHEREIN R2, R3, R4, AND R5 ARE SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, ALKYL OR 1 TO 3 CARBON ATOMS, INCLUSIVE, HALOGEN, NITRO, TRIFLUOROMETHYL, AND ALKOXY, ALKYLTHIO, ALKYLSULFINYL, ALKYLSULFONYL, IN WHICH CARBON CHAIN MOIETIES ARE OF 1 TO 3 CARBON ATOMS, INCLUSIVE, AND DIALKYLAMINO IN WHICH THE ALKYL GROUP IS DEFINED AS ABOVE; AND WHEREIN R6 IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, AND ALKYL DEFINED AS ABOVE, THE PRODUCED BY HEATING AN IMIDAZOLOBENZODIAZEPINE OF THE FORMULA I 1-R0,2-R1,4-R6,6-(R2,R3-PHENYL),R4,R5-4H-IMIDAZOLO(1,2-A)- 1,4-BENZODIAZEPINE WHEREIN R0, R1, R2, R3, R4, R5, AND R6 ARE DEFINED AS ABOVE WITH FORMIC ACID AND FORMALDEHYDE. THE COMPOUND OF FORMULA II AS WELL AS THE PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF ARE USEFUL AS SEDATIVES AND TRANQUILIZERS PARTICULARLY IN MAMMALS IN BIRDS.
Inventors
- 👤 M Gall
Bibliographic Details
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