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US3763137A Expired / Lapsed US ⏱️ 0.0 years remaining

Isolation of orgotein from red blood cells

Assignee: GT Biopharma Inc
•
Filing: 1971-12-07
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Granted: 1973-10-02
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Expires: 1991-12-07
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Abstract

Abstract SUBSTANTIALLY PURE ORGOTEIN IS OBTAINED IN A SIMGLE CHROMATOGRAPHIC PURIFICATION STEP FROM THE MIXTURE OF SOLUBLE PROTEINS PRESENT IN BOVINE, HUMAN OR OTHER RED BLOOD CELLS BY CHROMATOGRAPHING AN AQUEOUS SOLUTION OF THE MIXTURE OF PROTEIN HAVING A PH OF ABOUT 6 AND AN IONIC STRENGTH BELOW ABOUT 0.01 M OVER A DEAE-CELLULOSE OR OTHER WEAKLY BASIC ION EXCHANGE COLUMN; WASHING THE COLUMN FREE OF HEMOGLOBIN; SELECTIVELY ELUTING THE ADSORBED ORGOTEIN AT A HIGHER IONIC STRENGTH; AND SEPARATING ORGOTEIN FROM THAT PORTION OF THE ELUATE HAVING THE MAXIMUM DIVALENT METAL CONTENT.

Inventors

  • 👤 W Huber
  • 👤 A Huebner
  • 👤 M Saifer

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 16:35
CPC Classifications
C; C12; C12N; C12N9/00; C12N9/0004; C12N9/0089; B; B01; B01J; B01J41/00; B01J41/20; A; A61; A61K; A61K38/00; Y; Y10; Y10S; Y10S530/00; Y10S530/827; Y10S530/829

Claims Analysis

Total Claims: 0
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References Cited (Backward Citations)

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1976-10-01 1977-04-02 1977-10-02 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1980-10-01 1981-04-02 1981-10-02 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1984-10-01 1985-04-02 1985-10-02 $7700.00 Window Closed / Lapsed

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