US3763137A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Isolation of orgotein from red blood cells
Assignee: GT Biopharma Inc
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Filing: 1971-12-07
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Granted: 1973-10-02
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Expires: 1991-12-07
Abstract
Abstract SUBSTANTIALLY PURE ORGOTEIN IS OBTAINED IN A SIMGLE CHROMATOGRAPHIC PURIFICATION STEP FROM THE MIXTURE OF SOLUBLE PROTEINS PRESENT IN BOVINE, HUMAN OR OTHER RED BLOOD CELLS BY CHROMATOGRAPHING AN AQUEOUS SOLUTION OF THE MIXTURE OF PROTEIN HAVING A PH OF ABOUT 6 AND AN IONIC STRENGTH BELOW ABOUT 0.01 M OVER A DEAE-CELLULOSE OR OTHER WEAKLY BASIC ION EXCHANGE COLUMN; WASHING THE COLUMN FREE OF HEMOGLOBIN; SELECTIVELY ELUTING THE ADSORBED ORGOTEIN AT A HIGHER IONIC STRENGTH; AND SEPARATING ORGOTEIN FROM THAT PORTION OF THE ELUATE HAVING THE MAXIMUM DIVALENT METAL CONTENT.
Inventors
- 👤 W Huber
- 👤 A Huebner
- 👤 M Saifer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 07:33
CPC Classifications
C; C12; C12N; C12N9/00; C12N9/0004; C12N9/0089; B; B01; B01J; B01J41/00; B01J41/20; A; A61; A61K; A61K38/00; Y; Y10; Y10S; Y10S530/00; Y10S530/827; Y10S530/829
Claims Analysis
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References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1976-10-01 | 1977-04-02 | 1977-10-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1980-10-01 | 1981-04-02 | 1981-10-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1984-10-01 | 1985-04-02 | 1985-10-02 | $7700.00 | Window Closed / Lapsed |