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Process and intermediates in the preparation of eburnamonine

Assignee: Sanofi Aventis France
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Filing: 1971-12-28
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Granted: 1973-08-21
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Expires: 1991-12-28
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Abstract

Abstract THE OBJECT OF THIS INVENTION IS A NEW PROCESS OF PREPARATION OF ($) EBURNAMONINE OF THE FORMULA: 12-(O=),13A-(CH3-CH2-)-2,3,4A,5,6,12,13,13A-OCTAHYDRO- 1H-INDOLO(3,2,1-DE)PYRIDO(3,2,1-IJ)(1,5)NAPHTHYRIDINE IT IS KNOWN THAT EBURANAMONINE HAS BEEN ISOLATED FROM SEVERAL PLANT SPECIES SUCH AS VINCA MINOR AND HUNTERIA EBURNEA. EBURNAMONINE POSSESSES INTERESTING PHARMACOLOGICAL PROPERIES, IT PROVOKES A HYPERTENSION ACCOMPANIED BY A RESPIRATORY AND CARDIAC STIMULATION AND AN INCREASE OF TONICITY. IN ADDITION, EBURNAMONINE CAN SERVE AS STARTING MATERIAL IN THE SYNTHESIS OF KNOWN ANALOGOUS COMPOUNDS DISPLAYING AN INTERESTING PHYSIOLOGICAL ACTIVITY.

Inventors

  • 👤 J Martel
  • 👤 G Costerousse

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 19:03
CPC Classifications
C; C07; C07D; C07D471/00; C07D471/12; C07D471/14; C07D461/00

Claims Analysis

Total Claims: 0
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References Cited (Backward Citations)

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1976-08-20 1977-02-19 1977-08-21 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1980-08-20 1981-02-19 1981-08-21 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1984-08-20 1985-02-19 1985-08-21 $7700.00 Window Closed / Lapsed

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