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Patent US3751277A successfully refreshed from Google Patents.
US3751277A
Expired / Lapsed
US
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Tablet coating process and composition
Assignee: Dow Chemical Co
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Filing: 1971-03-24
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Granted: 1973-08-07
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Expires: 1991-03-24
Abstract
Abstract A composition for coating tablets and other individual dosage forms comprising a sugar, hydrolyzed cereal solids, starch, a solid polyethylene glycol and a liquid polyhydroxy organic compound is disclosed. The composition can be employed to coat tablets by applying aqueous solutions thereof to the tablets and drying the solvent.
Inventors
- 👤 J Small
- 👤 S Jeffries
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 16:54
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/28; A61K9/2806; A61K9/2833; A61K9/286; A61K9/282; A61K9/2826; A61K9/2853; C; C08; C08L; C08L3/00
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
10 words
The composition of claim 1 wherein the sugar is sucrose.
Claim 2
Dependent Claim
12 words
The composition of claim 1 wherein the polyhydroxy compound is propylene glycol.
Claim 3
Dependent Claim
21 words
The composition of claim 1 wherein the solid polyethylene glycol has a molecular weight of from about 6,000 to about 7,500.
Claim 4
Dependent Claim
61 words
The composition of claim 1 wherein the cereal starch solids hydrolysate has a dextrose equivalent of from about 10 to about 13 and contains from about 0.5 to about 1 percent dextrose, from about 4.5 to about 5 percent Disaccharides, from about 4.75 to about 5.5 percent trisaccharides and from about 3.75 to about 4.5 percent each of tetrasaccharides and pentasaccharides.
Claim 5
Dependent Claim
219 words
A coated tablet having as the coating material a thin film consisting of about 8 to about 25 percent by weight of a sugar selected from the group consisting of sucrose and lactose; from about 25 to about 55 percent by weight of pregelatinized starch; from about 7 to about 22 percent by weight of a solid, water-soluble polyethylene glycol having a molecular weight of from about 5,500 to about 8,000; from about 3 to about 8 percent by weight of a liquid polyhydroxy compound selected from the group consisting of propylene glycol, glycerin and a lower polyethylene glycol having a pour point below about 85*F.; and from about 15 to about 40 percent by weight of a cereal starch solids hydrolysate having a dextrose equivalent of from about 8 to about 20 and containing from about 0.5 to about 2 percent dextrose, from about 4.5 to about 8.5 percent disaccharides, from about 5 to about 10 percent trisaccharides, from about 3.7 to about 6 percent tetrasaccharides and from about 3.7 to about 5.5 percent pentasaccharides, said hydrolysate being sufficiently water-soluble to form a 50 percent solids by weight solution in water; and said hydrolysate being further characterized in that aqueous solutions thereof have a pH of from about 4.5 to about 5.5, as the sole essential film-forming ingredients.
Claim 6
Dependent Claim
90 words
The coated tablet of claim 6 wherein the sugar is sucrose, wherein the solid polyethylene glycol has a molecular weight of from about 6,000 to about 7,500, wherein the polyhydroxy compound is propylene glycol and wherein the cereal starch solids hydrolysate has a dextrose equivalent of from about 10 to 13 and contains from about 0.5 to about 1 percent dextrose, from about 4.5 to about 5 percent disaccharides, from about 4.75 to about 5.5 percent trisaccharides and from about 3.75 to about 4.5 percent each of tetrasaccharides and pentasaccharides.
Claim 7
Independent Claim
253 words
The method of coating tablets and the like which comprises applying to said tablets a coating composition consisting essentially of about 8 to about 25 percent by weight of a sugar selected from the group consisting of sucrose and lactose; from about 25 to about 55 percent by weight of pregelatinized starch; from about 7 to about 22 percent by weight of a solid, water-soluble polyethylene glycol having a molecular weight of from about 5,500 to about 8,000; from about 3 to about 8 percent by weight of a liquid polyhydroxy compound selected from the group consisting of propylene glycol, glycerin and a lower polyethylene glycol having a pour point below about 85*F.; and from about 15 to about 40 percent by weight of a water soluble cereal starch solids hydrolysate having a dextrose equivalent of from about 8 to about 20 and containing from about 0.5 to about 2 percent dextrose, from about 4.5 to about 8.5 percent disaccharides, from about 5 to about 10 percent trisaccharides, from about 3.7 to about 6 percent tetrasaccharides and from about 3.7 to about 5.5 percent pentasaccharides; said hydrolysate being sufficiently water-soluble to form a 50 percent solids by weight solution in water; and said hydrolysate being further characterized in that aqueous solutions thereof have a pH of from about 4.5 to about 5.5; the coating composition being applied in the form of a solution thereof in an aqueous solvent, the solution containing from about 10 to about 50 percent (weight/volume) of the coating composition.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1976-08-06 | 1977-02-05 | 1977-08-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1980-08-06 | 1981-02-05 | 1981-08-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1984-08-06 | 1985-02-05 | 1985-08-07 | $7700.00 | Window Closed / Lapsed |