Product of alpha monolithiated amine and carbonyl compounds

Abstract

Abstract A METHOD FOR FORMING AN AMINE ADDUCT OF A COMPOUND THAT REACTS IN A "GRIGNARD" MANNER, SAID METHOD COMPRISING THE STEP OF REACTING AN ALPHA MONO LITHIATED AMINE, SAID AMINE BEING CHARACTERIZED BY ONE OF THE FOLLOWING STRUCTURAL FORMULAE: (R)2-N-A-(N(-R)-A)X-N(-R)-CH(-LI)-R, (R)2-N-CH(-LI)-R, OR (-CH2-(CH2)Y-CH2-)>N-A-N<(-CH2-(CH2)Y-CH(-LI)-) WHEREIN R CAN BE THE SAME OR DIFFERENT AND IS A C1-C10 ALKYL, X ISAN INTEGER OF 0 TO 10,000, Y IS AN INTEGER OF 0 TO 3, AND A IS A RADICAL WHICH IS (1) A CYCLOALIPHATIC RADICAL OR A CYCLOALIPHATIC RADICAL CONTAINING C1-C4 ALKYL GROUPS, SAID RADICALS HAVING RING STRUCTURES OF 4 TO 7 MEMBERS AND BEING ATTACHED TO THE NITROGEN ATOMS AT 1,2 OR 1,3 POSITIONS ON SAID RING, OR (2) A RADICAL CONSISTING OF 1 TO 20 METHYLENIC GROUPS WHEREIN EACH METHYLENIC GROUP CONTAINS 0 TO 2 MONOVALENT HYDROCARBON RADICALS OF 1 TO 6 CARBON ATOMS, WITH A COMPOUND THAT REACTS IN A "GRIGNARD" MANNER UNDER CONDITIONS OF TEMPERATURE, CONCENTRATIONS OF REACTANTS AND PRESSURES SUFFICIENT TO FORM SAID AMINE ADDUCT. IN ADDITION, THIS INVENTION RELATES TO A METHOD FOR PREPARING AN OGANO-LITHIUM AMINE COMPLEX WHICH COMPRISES ADMIXING A LITHIATED AMINE SIMILAR TO THE ONE DESCRIBED HEREINABOVE WITH A HYDROCARBON GROUP-CONTAINING COM POUND HAING AN ACIDITY CORRESPONDING TO A PKA OF NOT MORE THAN 38.

Inventors

• 👤 A Langer

Bibliographic Details