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Patent US3728351A successfully refreshed from Google Patents.
US3728351A
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Radioiodinated quinoline derivatives
Assignee: University of Michigan (System)
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Filing: 1968-05-31
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Granted: 1973-04-17
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Expires: 1988-05-31
Abstract
Abstract Radioiodinated analogs of 4-substituted-7-iodoquinolines when administered parenterally or orally are selectively concentrated in animal tissues containing melanin and may be used for the detection and location of melanotic tumors as well as other abnormal growths. The preferred quinoline compounds are 4(dialkylaminoalkylamino)-7-iodoquinolines, such as for example 4(3-dimethylaminopropylamino)-7-iodoquinoline. The radioiodinated compounds are prepared by isotope exchange between the natural iodinated compounds and radioactive alkali metal iodides.
Inventors
- 👤 R Counsell
- 👤 P Mehta
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 13:09
CPC Classifications
C; C07; C07D; C07D215/00; C07D215/02; C07D215/16; C07D215/20; C07D215/22; C07D215/233; C07D215/38; C07D215/42; C07D215/46
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
5 words
A compound having the formula:
Claim 2
Dependent Claim
11 words
A compound according to claim 2 in which n is 3.
Claim 3
Dependent Claim
17 words
A compound according to claim 1 in which R1 is hydrogen and R2 is the radical 4-methylpentyl.
Claim 4
Dependent Claim
15 words
A compound according to claim 1 in which both R1 and R2 are methyl radicals.
References Cited (Backward Citations)
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Cited
US2554316A
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US2911338A
Cited
US3091571A
Cited
US3145197A
Cited
US3339072A
Cited
US3406176A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1976-04-16 | 1976-10-16 | 1977-04-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1980-04-16 | 1980-10-16 | 1981-04-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1984-04-16 | 1984-10-16 | 1985-04-17 | $7700.00 | Window Closed / Lapsed |