Abstract Novel anti-atherosclerosis agents having the formula, WHEREIN TYPICAL EXAMPLES OF R1 and R2 are hydrogen, C1-C8 alkyl, phenyl, benzyl and phenethyl, or R1 and R2 may form cycloalkylidene together with a carbon atom bonded therewith; R3 and R4 each is hydrogen or C1-C4 alkyl; Y is hydroxyl, C1-C4 alkoxy, phenoxy or an amine residue; A is hydrogen or a group of the formula, WHEREIN R3, R4 and Y have the same meanings as defined above; and D and E each is hydrogen or halogen. These compounds are produced, for example, by reacting a bisphenolic compound of the formula, in the presence of an alkali. Alternatively, they are produced by reacting the bisphenolic compound with Alpha -halogeno- or Alpha -hydroxycarboxylic acid derivative of the formula, WHEREIN R1, R2, R3, R4, D, E and Y have the same meanings as defined above; and X is halogen or hydroxyl.