1-(2-or 3-(4-(10,11-dihydro-dibenz(b,f)-thiepin-10-yl)-1-piperazinyl)-alkyl)-3-alkyl-2-imidazolidinone derivatives
Abstract
Abstract COMPOUNDS OF THE CLASS 1-(2- OR 3-(4-(10,11-DIHYDRODIBENZ(B,F) - THIEPIN-10-YL)-1-PIPERAZINYL)-ALKYL)-3-ALKYL2-IMIDAZLIDINONE WHICH CAN BE SUBSTITUTED IN 8-POSITION OF THE DIBENZO(B,F)THIEPINE MOIETY BY CHLORO, METHYL, TRIFLUOROMETHYL, METHOXY OR METHYLTHIO AND THE PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF, HAVE A DEPRESSANT EFFECT ON THE CENTRAL NERVOUS SYSTEM; PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS AND METHODS OF TREATMENT, PARTICULARLY METHODS OF INDUCING A DEPRESSANT EFFECT IN WARM-BLOODED ANIMALS ARE PROVIDED; AN ILLUSTRATIVE EMBODIMENT IS 1-(2-(4-(8-CHLORO-10,11-HIHYDRODIBENZO(B,F)THIEPIN-10-YL) - 1 - PIPERAZINYL)-ETHYL)-3METHYL-2-IMIDAZOLIDINONE.
Inventors
- 👤 Walter Schindler
- 👤 Erich Schmid
- 👤 Armin Zuest
Bibliographic Details
Claims Analysis
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