Patent US3689514A successfully refreshed from Google Patents.
US3689514A
Expired / Lapsed
US
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Suppository vehicle and process of making same
Assignee: DANSK SOJAKAGEFABRIK/DS INDUSTRIES APA
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Filing: 1969-05-21
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Granted: 1972-09-05
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Expires: 1989-05-21
Abstract
Abstract The suppository vehicle material of this invention consists of hard fat, the hydroxyl number of which has been reduced to less than 10 and preferably to less than 3, by esterification of the free hydroxyl groups of said hard fat with mono-alkanoic acids with one to eight carbon atoms. Such suppository vehicle material is especially suitable for preparing suppositories with drugs having acid groups, such as acetyl salicylic acid. The resulting suppositories are stable even on prolonged storage and at deep freeze temperatures, do not become brittle, have a sharp melting point, and solidify rapidly and completely in suppository molds.
Inventors
- 👤 Rudolf Neissner
- 👤 Eckhard Schulz
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 11:41
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/02; C; C11; C11C; C11C3/00; C11C3/04
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
28 words
Suppository vehicle material according to claim 1, wherein the hard fat is a mixture of mono-, di-, and triglycerides of fatty acids with 12 to 18 carbon atoms.
Claim 2
Dependent Claim
19 words
Suppository vehicle material according to claim 1, wherein the esterified hard fat has a hydroxyl number of about zero.
Claim 3
Dependent Claim
22 words
Suppository vehicle material according to claim 1, wherein the melting point of the esterified hard fat is between 34.0* and 35.0* C.
Claim 4
Dependent Claim
14 words
Suppository vehicle material according to claim 1, wherein the mono-alkanoic acid is acetic acid.
Claim 5
Dependent Claim
14 words
Suppository vehicle material according to claim 1, wherein the mono-alkanoic acid is propionic acid.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1975-09-05 | 1976-03-06 | 1976-09-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1979-09-05 | 1980-03-06 | 1980-09-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1983-09-05 | 1984-03-06 | 1984-09-05 | $7700.00 | Window Closed / Lapsed |