Patent US3686393A successfully refreshed from Google Patents.
US3686393A
Expired / Lapsed
US
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Method for inhibiting dental plaque
Assignee: Merck and Co Inc
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Filing: 1970-02-12
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Granted: 1972-08-22
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Expires: 1990-02-12
Abstract
Abstract The enzyme dextranase is applied to the teeth and gums to eliminate or suppress plaque formation.
Inventors
- 👤 Harold Boyd Woodruff
- 👤 Thomas H Stoudt
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 19:44
CPC Classifications
C; C12; C12N; C12N9/00; C12N9/14; C12N9/24; C12N9/2402; C12N9/2405; C12N9/2451; C12N9/2454
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
67 words
The method of eliminating dental plaque formation which comprises applying to teeth having plaque thereon, per unit dosage, from 1,000 to 200,000 units of dextranase produced by growing P. funiculosum NRRL 1768 in a fermentation broth therefor at a suitable temperature for a suitable period of time and separating therefrom an enzyme having from 100 to 2,000 dextranase units of activity per milliliter of the fermentation broth.
Claim 2
Independent Claim
67 words
The method of eliminating dental plaque formation which comprises applying to teeth having plaque thereon, per unit dosage, from 1,000 to 200,000 units of dextranase produced by growing P. funiculosum NRRL 896 in a fermentation broth therefor at a suitable temperature for a suitable period of time and separating therefrom an enzyme having from 100 to 2,000 dextranase units of activity per milliliter of the fermentation broth.
Claim 3
Independent Claim
67 words
The method of eliminating dental plaque formation which comprises applying to teeth having plaque thereon, per unit dosage, from 1,000 to 200,000 units of dextranase produced by growing P. funiculosum NRRL 2135 in a fermentation broth therefor at a suitable temperature for a suitable period of time and separating therefrom an enzyme having from 100 to 2,000 dextranase units of activity per milliliter of the fermentation broth.
Claim 4
Independent Claim
67 words
The method of eliminating dental plaque formation which comprises applying to teeth having plaque thereon, per unit dosage, from 1,000 to 200,000 units of dextranase produced by growing Fungal Isolate NRRL 3673 in a fermentation broth therefor at a suitable temperature for a suitable period of time and separating therefrom an enzyme having from 100 to 2,000 dextranase units of activity per milliliter of the fermentation broth.
References Cited (Backward Citations)
GB941664A
Cited
US3194738A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1975-08-22 | 1976-02-21 | 1976-08-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1979-08-22 | 1980-02-21 | 1980-08-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1983-08-22 | 1984-02-21 | 1984-08-22 | $7700.00 | Window Closed / Lapsed |