Phenyl benzofuran acetic acid compounds

Abstract

Abstract 3-Phenyl-7-benzofuranacetic acids, 4-phenyl-7-benzofuranacetic acids, 7-phenyl-4-benzofuranacetic acids, 2-methyl-7-phenyl-4benzofuranacetic acids, and 7-phenyl-3-benzofuranacetic acids, optionally substituted in the phenyl group by fluorine or chlorine and on the Alpha -carbon group by lower alkyl; carboxylate salts thereof; and their production by hydrolysis of a correspondingly substituted carboxylic acid precursor or by decarboxylation by heating of a malonic acid precursor. The compounds of the invention are useful as anti-inflammatory agents.

Inventors

• 👤 James S Kaltenbronn
• 👤 Franklin W Short

Bibliographic Details