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US3679653A
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Hormonally-active reaction product of a polymer with a hormone
Assignee: Monsanto Co
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Filing: 1968-09-27
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Granted: 1972-07-25
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Expires: 1988-09-27
Abstract
Abstract A HORMONOALY-ACITVE REACTION PRODUCT OF A PEPTIDIC HORMONE SUCH AS BOVINE GROWTH HORMONE, INSULIN, VASOPRESSIN, ADRENOCORTICOTROPIC HORMONE, AND THE LIKE, WITH A COPOLYMER OF AN OLEFINICALLY UNSATURATED POLYCARBOXYLIC ACID AND AN OLEFIN. THE HORMONE IS COVALENTLY BOUND TO THE POLYMER THROUGH AN AMINO, HYDROXYL, OR SULFHYDRYL GROUP OF THE HORMONE WHICH IS NOT ESSENTIAL FOR HORMONAL ACITIVITY. THESE PRODUCTS HAVE IMPROVED STABILITY, ARE SUBSTANTIALLY ODORLESS AND COLORLESS, AND HAVE PROLONGED ACITIVITY WHEN CONTRASTED WITH THE NATIVE HORMONE.
Inventors
- 👤 James M Schuck
- 👤 Bernard S Wildi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 22:08
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/22; A61K38/27; A61K38/04; A61K38/08; A61K38/095; A61K38/28; A61K38/33; A61K38/35; A61K47/00; A61K47/50; A61K47/51; A61K47/56; A61K47/58; Y; Y10; Y10S; Y10S530/00; Y10S530/81; Y10S530/812; Y10S530/815
Claims Analysis
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References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1975-07-25 | 1976-01-24 | 1976-07-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1979-07-25 | 1980-01-24 | 1980-07-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1983-07-25 | 1984-01-24 | 1984-07-25 | $7700.00 | Window Closed / Lapsed |