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US3676554A
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Anti-arthritic compositions comprising phosphine or phosphite gold halide complexes and methods of producing anti-arthritic activity
Assignee: Smith Kline & French Laboratories Ltd
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Filing: 1970-10-30
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Granted: 1972-07-11
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Expires: 1990-10-30
Abstract
Abstract Pharmaceutical compositions having anti-arthritic activity comprising a phosphine or phosphite gold halide complex and methods of producing anti-arthritic activity by administering internally, preferably orally, said compositions.
Inventors
- 👤 Elizabeth R Mcgusty
- 👤 Blaine M Sutton
- 👤 Donald T Walz
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 14:04
CPC Classifications
C; C07; C07F; C07F9/00; C07F9/02; C07F9/28; C07F9/50; C07F9/5045
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
12 words
A pharmaceutical composition according to claim 1 in which X is chloro.
Claim 2
Dependent Claim
13 words
A pharmaceutical composition according to claim 2 in which R is lower alkyl.
Claim 3
Dependent Claim
12 words
A pharmaceutical composition according to claim 3 in which R is ethyl.
Claim 4
Dependent Claim
28 words
A pharmaceutical composition according to claim 4 in which the amount of the active medicament is from about 1 mg. to about 5 mg., calculated on gold content.
Claim 5
Independent Claim
75 words
The method of producing anti-arthritic activity which comprises administering orally to an animal organism in an amount sufficient to produce said activity without limiting side effects a phosphine or phosphite gold halide complex of the formula: R3P -> AuX in which: R is lower alkyl, phenyl, lower alkoxy or phenoxy, said lower alkyl and lower alkoxy being straight or branched chain, of from one to three carbon atoms; and X is chloro, bromo or iodo.
Claim 6
Dependent Claim
11 words
The method according to claim 6 in which X is chloro.
Claim 7
Dependent Claim
12 words
The method according to claim 7 in which R is lower alkyl.
Claim 8
Dependent Claim
11 words
The method according to claim 8 in which R is ethyl.
Claim 9
Dependent Claim
31 words
The method according to claim 9 in which the active medicament is administered in a daily dosage regimen of from about 1 mg. to about 10 mg., calculated on gold content.
References Cited (Backward Citations)
US2451841A
Cited
US2607789A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1975-07-11 | 1976-01-10 | 1976-07-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1979-07-11 | 1980-01-10 | 1980-07-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1983-07-11 | 1984-01-10 | 1984-07-11 | $7700.00 | Window Closed / Lapsed |