Patent US3673218A successfully refreshed from Google Patents.
US3673218A
Expired / Lapsed
US
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Bichromonyl compounds
Assignee: Fisons Pharmaceuticals Ltd
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Filing: 1969-10-28
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Granted: 1972-06-27
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Expires: 1989-10-28
Abstract
Abstract Compounds of the formula IN WHICH P to T1 are hydrogen, alkyl, alkoxy, alkenyl, alkenyloxy, substituted alkyl, substituted alkoxy, substituted alkenyl, substituted alkenyloxy, amino, substituted amino aminoalkoxy, substituted aminoalkoxy, nitro, halo, hydroxy, or benzyloxy; the R1 groups are hydrogen, substituted or unsubstituted alkyl, alkoxy or aryl; and X is a carbon - carbon bond or a single atom, which may be substituted, through which the chromone nuclei are linked, and pharmaceutically acceptable derivatives thereof, are indicated for use in the treatment of ''extrinsic'' allergic asthma.
Inventors
- 👤 Hugh Cairns
- 👤 Peter Bennett Johnson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 15:04
CPC Classifications
C; C07; C07D; C07D311/00; C07D311/02; C07D311/04; C07D311/22; C07D311/24; C07C; C07C45/00; C07C45/45; C07C45/46; C07C45/51; C07C45/54; C07C45/61; C07C45/63; C07C45/67; C07C45/68; C07C45/70; C07C45/71; C07C49/00; C07C49/76; C07C49/82; C07C49/825; C07C49/835; C07C59/00; C07C59/40; C07C59/58; C07C59/64; C07C59/66; C07C59/68; C07C59/76; C07C59/90; C07D213/00; C07D213/02; C07D213/04; C07D213/24; C07D213/44; C07D213/46; C07D213/50
Claims Analysis
Total Claims: 33
Claim 1
Independent Claim
38 words
A compound according to claim 1, wherein X is a carbon-carbon bond; a sulphur or oxygen atom, or a group -CH2-, -CHOH-, -C(R4)2-, -CO-, -CH(COOH)-, -CH(COOR4)-, , -NH-, -SO- or -SO2-, and R4 represents a lower alkyl group.
Claim 2
Dependent Claim
12 words
A compound according to claim 1, wherein both R1 groups are hydrogen.
Claim 3
Dependent Claim
29 words
A compound according to claim 1, wherein X is a carbon -carbon bond or an -NH- group, which bond or group links the 6,6'' positions of the chromone nuclei.
Claim 4
Dependent Claim
36 words
A compound according to claim 1, wherein -X- links the same positions on each chromone nucleus and is a carbon - carbon bond, a sulphur or oxygen atom, or a group -SO2-, -CH(COOH)-, -CH(COOC2H5)-, , -CH2-,
Claim 5
Dependent Claim
15 words
A compound according to claim 1 in the form of a pharmaceutically acceptable salt thereof.
Claim 6
Dependent Claim
35 words
A compound according to claim 6 wherein the salt is selected from salts having an alkaline earth, alkali-metal, piperidinium, pyridinium or mono- di- or tri-lower alkyl or lower alkanol ammonium cation, or the ammonium cation.
Claim 7
Dependent Claim
13 words
A compound according to claim 7, wherein the salt is the sodium salt.
Claim 8
Dependent Claim
15 words
A compound according to claim 5 in the form of a pharmaceutically acceptable salt thereof.
Claim 9
Dependent Claim
11 words
A compound according to claim 1 which is 2,2''-dicarboxy 6, 6''-bichromonyl.
Claim 10
Dependent Claim
10 words
A compound according to claim 1 which is 2,2''-dicarboxy-5, 5''-dimethoxy-6,6''-bichromonyl.
Claim 11
Dependent Claim
9 words
A compound according to claim 1 which is bis-(7-benzyloxy-2-carboxychromon-6-yl)sUlphide.
Claim 12
Dependent Claim
11 words
A compound according to claim 1 which is 2,2''-dicarboxy-5, 5'', 7,7''-tetramethoxy-8,8''-bichromonyl.
Claim 13
Dependent Claim
10 words
A compound according to claim 1 which is 2,2''-dicarboxy-7, 7''-dimethoxy-8,8''-bichromonyl.
Claim 14
Dependent Claim
10 words
A compound according to claim 1 which is 2,2''-dicarboxy-6, 6''-dimethoxy-5,5''-bichromonyl..
Claim 15
Dependent Claim
9 words
A compound according to claim 1 which is bis-(2-carboxy-5-methoxychromon-8-yl)sulphide.
Claim 16
Dependent Claim
9 words
A compound according to claim 1 which is bis-(2-carboxychromon-6-yl)sulphide.
Claim 17
Dependent Claim
9 words
A compound according to claim 1 which is bis-(2-carboxy-7-methoxychromon-6-yl)sulphide.
Claim 18
Dependent Claim
9 words
A compound according to claim 1 which is bis-(2-carboxy-7-methoxychromon-6-yl)sulphone.
Claim 19
Dependent Claim
10 words
A compound according to claim 1 which is 2,2''-dicarboxy-7, 7''-bichromonyl.
Claim 20
Dependent Claim
9 words
A compound according to claim 1 which is bis-(2-carboxychromon-6-yl)ether.
Claim 21
Dependent Claim
9 words
A compound according to claim 1 which is bis-(2-carboxy-5-methoxychromon-8-yl)sulphone.
Claim 22
Dependent Claim
9 words
A compound according to claim 1 which is 6,6''-dibromo-2,2''-dicarboxy-8,8''-bichromonyl.
Claim 23
Dependent Claim
11 words
A compound according to claim 1 which is 2,2''-bis-(2-carbocychromon-6-yl) acetic acid.
Claim 24
Dependent Claim
10 words
A compound according to claim 1 which is ethyl 2,2''-bis-(2-carboxychromon-6-yl)acetate.
Claim 25
Dependent Claim
9 words
A compound according to claim 1 which is 1,1''-bis-(2-carboxychromon-6-yl)-2,2-dichloroethylene.
Claim 26
Dependent Claim
11 words
A compound according to claim 1 which is bis-(2-carboxychromon-6-yl) pyrid-2-yl methane.
Claim 27
Dependent Claim
10 words
A compound according to claim 1 which is bis-(2-carboxychromon-6-yl) methane.
Claim 28
Dependent Claim
10 words
A compound according to claim 1 which is bis-(2-carboxy-7-(2-hydroxypropoxy)chromon-8-yl) methane.
Claim 29
Dependent Claim
10 words
A compound according to claim 1 which is 2,2''-bis-(2-carboxychromon-6-yl) propane.
Claim 30
Dependent Claim
10 words
A compound according to claim 1 which is bis-(2-carboxychromon-6-yl) ketone.
Claim 31
Dependent Claim
10 words
A compound according to claim 1 which is bis-(2-carboxychromon-8-yl) methane.
Claim 32
Dependent Claim
10 words
A compound according to claim 1 which is di-(2-carboxychromon-6-yl) amine.
Claim 33
Dependent Claim
10 words
A compound according to claim 1 which is 2,2''-dicarboxy-8, 8''-bichromonyl.
References Cited (Backward Citations)
US3419578A
Cited
US3519652A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1975-06-27 | 1975-12-27 | 1976-06-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1979-06-27 | 1979-12-27 | 1980-06-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1983-06-27 | 1983-12-27 | 1984-06-27 | $7700.00 | Window Closed / Lapsed |