Patent US3668208A successfully refreshed from Google Patents.
US3668208A
Expired / Lapsed
US
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Hexahydro imidazoquinolines
Assignee: Pfizer Inc
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Filing: 1970-02-13
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Granted: 1972-06-06
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Expires: 1990-02-13
Abstract
Abstract A series of novel substituted hexahydro imidazoquinoline compounds have been prepared from the corresponding 2aminomethyl-1,2,3,4-tetrahydroisoquinolines. These compounds are useful in the field of chemotherapy as anti-schistosomal agents. Preferred members include 2-(lower alkyl)-7-methyl-8-nitro1,2,3,3a,4,5-hexahydroimidazo-(1,5-a)-quinolines, 2-(lower alkyl)-7-hydroxymethyl-8-nitro-1,2,3,3a,4,5-hexahydroimidazo(1,5-a) -quinolines and 2-(lower alkyl)-7-methyl-8-chloro1,2,3,3a,4,5-hexahydroimidazo-(1,5-a)-quinolines, as well as various 1- and 9-substituted derivatives thereof.
Inventors
- 👤 Charles A R Baxter
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 20:39
CPC Classifications
C; C07; C07D; C07D471/00; C07D471/02; C07D471/04
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
32 words
A compound as claimed in claim 1 wherein R1 is alkyl having from one to six carbon atoms, R2 is methyl, R3 is nitro, and R4, R5 and R6 are each hydrogen.
Claim 2
Dependent Claim
34 words
A compound as Claimed in claim 1 wherein R1 is alkyl having from one to six carbon atoms, R2 and R5 are each methyl, R3 is chlorine, and R4 and R6 are each hydrogen.
Claim 3
Dependent Claim
32 words
A compound as claimed in claim 1 wherein R1 is alkyl having from one to six carbon atoms, R2 is hydroxymethyl, R3 is nitro, and R4, R5 and R6 are each hydrogen.
Claim 4
Dependent Claim
34 words
A compound as claimed in claim 1 wherein R1 and R6 are each alkyl having from one to six carbon atoms, R2 is methyl, R3 is nitro, and R4 and R5 are each hydrogen.
Claim 5
Dependent Claim
34 words
A compound as claimed in claim 1 wherein R1 is alkyl having from one to six carbon atoms, R2 is methyl, R3 is nitro, R4 and R5 are each hydrogen, and R6 is phenyl.
Claim 6
Dependent Claim
34 words
A compound as claimed in claim 1 wherein R1 is alkyl having from one to six carbon atoms, R2 is methyl, R3 is nitro, R4 and R5 are each hydrogen, and R6 is nitrophenyl.
Claim 7
Dependent Claim
34 words
A compound as claimed in claim 1 wherein R1 is alkyl having from one to six carbon atoms, R2 is methyl, R3 is nitro, R4 and R5 are each hydrogen and R6 is thienyl.
Claim 8
Dependent Claim
15 words
The compound as claimed in claim 3 wherein R1 is isopropyl and R5 is methyl.
Claim 9
Dependent Claim
10 words
The compound as in claim 4 wherein R1 is isopropyl.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1975-06-06 | 1975-12-06 | 1976-06-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1979-06-06 | 1979-12-06 | 1980-06-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1983-06-06 | 1983-12-06 | 1984-06-06 | $7700.00 | Window Closed / Lapsed |