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US3668076A Expired / Lapsed US ⏱️ 0.0 years remaining

Diagnostic agent

Assignee: Roche Diagnostics GmbH
•
Filing: 1969-06-17
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Granted: 1972-06-06
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Expires: 1989-06-17
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Abstract

Abstract Diagnostic agent suitable for use in carrying out rapid analytical determinations of the presence and/or concentration of hydroperoxides, substances which react with the liberation of hydrogen peroxide, peroxidase or peroxidate active substances, comprising a chromogen which is oxidized by hydroperoxide in the presence of peroxidase or peroxidate active substances to form a dyestuff, the color intensity of which is dependent on the quantity of peroxide, peroxidase or peroxidate active substance present in the test sample, wherein the chromogen is a compound having the formula: WHEREIN Y is hydroxyl, mercapto, or amino, Z is hydroxyl, wherein Y AND Z together can represent oxygen, and R is hydrogen, mercapto, amino, lower alkyl, pyridino, morpholino, piperazinyl, arylpiperazinyl, phenyl, or phenyl substituted by one or more of hydroxyl, nitro, alkyl or alkoxyl.

Inventors

  • 👤 Hans-Georg Rey
  • 👤 Hans Wielinger
  • 👤 Peter Rieckmann

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 20:00
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/26; C12Q1/28; C12Q1/54; C12Q2326/00; Y; Y10; Y10S; Y10S435/00; Y10S435/805; Y10S436/00; Y10S436/904; Y10T; Y10T436/00; Y10T436/14; Y10T436/142222; Y10T436/143333; Y10T436/144444; Y10T436/145555; Y10T436/147777; Y10T436/148888; Y10T436/20; Y10T436/206664

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 35 words
Diagnostic agent according to claim 1 having the formula: wherein Y'' is a member selected from the group consisting of oxygen, sulfur and imino, Z'' is oxygen and R is as defined in claim 1.
Claim 2
Dependent Claim 51 words
Diagnostic agent according to claim 1 for use in the determination of hydroperoxide, or a substance or mixture of substances which react with the liberation of hydrogen peroxide comprising a member selected from the group consisting of peroxidase and a peroxidate active substance and a chromogen as defined in claim 1.
Claim 3
Dependent Claim 39 words
Diagnostic agent according to claim 1 for use in the determination of peroxidate active substances comprising a member selected from the group consisting of hydrogen peroxide and substances forming hydrogen peroxide and a chromogen as defined in claim 1.
Claim 4
Dependent Claim 18 words
Diagnostic agent according to claim 1 in the form of a test paper impregnated with said diagnostic agent.
Claim 5
Dependent Claim 18 words
Diagnostic agent according to claim 1 in the form of a test film impregnated with said diagnostic agent.
Claim 6
Dependent Claim 13 words
Diagnostic agent according to claim 1 in the form of a solution thereof.
Claim 7
Dependent Claim 11 words
Diagnostic agent according to claim 1 wherein said chromogen is N-(2-hydroxy-3-methoxy-benzoyl)-N''-(pyridine-3-carbonyl)-hydrazine.
Claim 8
Dependent Claim 11 words
Diagnostic agent according to claim 1 wherein said chromogen is N-(2-hydroxy-3-methoxy-benzoyl)-N''-(pyridine-2-carbonyl)-hydrazine.

References Cited (Backward Citations)

US3233974A Cited
US3290228A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1975-06-06 1975-12-06 1976-06-06 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1979-06-06 1979-12-06 1980-06-06 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1983-06-06 1983-12-06 1984-06-06 $7700.00 Window Closed / Lapsed

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