Patent US4747124A successfully refreshed from Google Patents.
Patent US3666748A successfully refreshed from Google Patents.
US3666748A
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Method for production of cytidine (or deoxycytidine)-5{40 -diphosphate choline and intermediates therefor
Assignee: Takeda Pharmaceutical Co Ltd
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Filing: 1968-12-17
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Granted: 1972-05-30
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Expires: 1988-12-17
Abstract
Abstract Cytidine-5''-diphosphate choline and deoxycytidine-5''-diphosphate choline are produced by reacting cytidine (or deoxycytidine)-5''monophosphate with a choline phosphoramidate. Choline phosphoramidates of the formula WHEREIN R1 and R2 represent hydrogen, a hydrocarbon residue having at most seven carbon atoms, or R1 and R2 taken together represent a five- or six-membered heterocyclic ring are prepared by reacting phosphorylcholine with an amine.
Inventors
- 👤 Mikio Honjo
- 👤 Yoshiyasu Furukawa
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 16:47
CPC Classifications
C; C07; C07H; C07H19/00; C07H19/02; C07H19/04; C07H19/06; C07H19/10; C07F; C07F9/00; C07F9/02; C07F9/06; C07F9/22; C07F9/24
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
37 words
The method according to claim 1, wherein the cytidine- or deoxycytidine- 5''-monophosphate is in the form of an organic amine salt, said amine being selected from the group consisting of diethylamine, triethylamine, tributylamine, tri-n-octylamine, dicyclohexylguanidine and pyridine.
Claim 2
Dependent Claim
48 words
The method according to claim 1, wherein the amidate is of the formula wherein each of R1 and R2 represents hydrogen, a hydrocarbon residue having at most 7 carbon atoms, or R1 and R2, taken together with the adjacent nitrogen atom represent a five- or six-membered heterocyclic ring.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1975-05-30 | 1975-11-29 | 1976-05-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1979-05-30 | 1979-11-29 | 1980-05-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1983-05-30 | 1983-11-29 | 1984-05-30 | $7700.00 | Window Closed / Lapsed |