Certain benzofuran derivatives useful for relief of pain,inflammation,pyresis and tussive irritation

Abstract

Abstract The specification discloses benzofuran derivatives characterized by the formula: WHEREIN R represents a lower alkyl group, a phenyl group or a lower alkyl, lower alkoxy, dioxy-lower-alkylene, fluorine, chlorine, bromine or trifluoromethyl substituted phenyl group or a lower alkoxy substituted styryl group, R1 represents a hydrogen, fluorine, chlorine or bromine atom or a lower alkyl or lower alkoxy group, or together with R2 represents a benzo group, R2 represents a hydrogen, fluorine, chlorine or bromine atom or a lower alkyl or lower alkoxy group or provided R1 is a hydrogen atom, a nitro, amino, hydroxy, lower acyloxy, lower alkoxybenzoyloxy, lower dialkylamino or lower acylamino group, A represents an alkylene group containing not more than four carbon atoms, R3 represents a hydrogen atom or a lower alkyl group, R4 represents a lower alkyl, Beta -phenylethyl or benzyl group or NR3R4 represents a pyrrolidino, piperidino, hexamethyleneimino, morpholino, lower dialkylmorpholino, piperazino, lower alkyl piperazino, benzylpiperazino or tetrahydropyridino group, in the form of the free base or of a pharmaceutically acceptable salt thereof.

Inventors

• 👤 Arne Elof Brandstrom
• 👤 Stig Ake Ingemar Carlsson

Bibliographic Details