Patent US3640813A successfully refreshed from Google Patents.
US3640813A
Expired / Lapsed
US
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Adapter for a macromolecule separation device
Assignee: SAMUEL T NERENBERG
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Filing: 1969-06-09
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Granted: 1972-02-08
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Expires: 1989-06-09
Abstract
Abstract A device for adapting an upstanding column to separate macromolecules in preparative amounts by means of electrophoresis, chromatography and electrochromatography carried out in a granular or nongranular gel medium disposed in the column. One device contains an electrically conductive, selfsupporting gel disposed within a tubular housing adapted to sealingly engage the lower portion of the column. Channels may be provided in the adapter gel for fluid ingress to the upper gel surface and egress therefrom. A method for forming the adapter including electrophoresis and electrochromatography performed in a single column.
Inventors
- 👤 Samuel T Nerenberg
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 15:31
CPC Classifications
G; G01; G01N; G01N27/00; G01N27/26; G01N27/416; G01N27/447; G01N27/44704
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
13 words
A device as in claim 1 wherein said gel is an electrolyte-entrapping polymer.
Claim 2
Dependent Claim
13 words
A device as in claim 2 wherein said polymer is a cross-linked polyacrylamide.
Claim 3
Dependent Claim
22 words
A device as in claim 1 wherein said gel is formed from an electrolytic buffer solution containing about 10- 30% acrylamide monomer.
Claim 4
Dependent Claim
14 words
The device of claim 1 together with an outlet port in said tubular housing.
Claim 5
Dependent Claim
20 words
The device of claim 5 together with a passage from the upper gel surface to a position adjacent said port.
Claim 6
Dependent Claim
15 words
The device of claim 5 together with a separate inlet port in said tubular housing.
Claim 7
Dependent Claim
22 words
The device of claim 7 together with separate passages from the upper gel surface to positions adjacent said inlet and outlet ports.
Claim 8
Independent Claim
65 words
An apparatus for separating a mixture of macromolecules by means of electrophoresis, chromatography, or electrochromatography, said device comprising upstanding column means containing a separating medium, vertical adapter means sealingly engaged to a mating lower end of said column means, said adapter means comprising a tubular housing means containing an electrically conductive, self-supporting gel means, said gel forming a seal against liquid flow from the column.
Claim 9
Independent Claim
91 words
An apparatus for separating a mixture of macromolecules by means of electrophoresis, chromatography, or electrochromatography, said device comprising upstanding column means containing a separating medium, vertical adapter means sealingly engaged to a mating lower end of said column means, said adapter means comprising a tubular housing means containing an electrically conductive, self-supporting gel means, said gel means containing channel means interconnecting an opening in the wall of said housing with an opening at the top of said gel means wherein liquid flow from the column is directed through said channel means.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1975-02-07 | 1975-08-09 | 1976-02-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1979-02-07 | 1979-08-09 | 1980-02-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1983-02-07 | 1983-08-09 | 1984-02-08 | $7700.00 | Window Closed / Lapsed |