Patent US3627697A successfully refreshed from Google Patents.
US3627697A
Expired / Lapsed
US
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Hydroperoxide diagnostic agents containing a chromogen indicator
Assignee: Roche Diagnostics GmbH
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Filing: 1970-03-20
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Granted: 1971-12-14
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Expires: 1990-03-20
Abstract
Abstract D R A W I N G
Inventors
- 👤 Hans-Georg Rey
- 👤 Hans Wielinger
- 👤 Peter Rieckmann
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 16:18
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/54; C12Q1/26; C12Q1/28; C12Q2326/00; Y; Y10; Y10T; Y10T436/00; Y10T436/20; Y10T436/206664
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
52 words
Diagnostic agent as claimed in claim 1 for use in the determination of hydroperoxide or a substance wHich reacts with the liberation of hydrogen peroxide, which agent comprises (1) a member selected from the group consisting of peroxidase and a peroxidatively active substance, and (b) a chromogen as defined in claim 1.
Claim 2
Dependent Claim
69 words
Diagnostic agent as claimed in claim 2 additionally containing a modifier compound having the formula: wherein Ar is a benzene or naphthalene nucleus; V is amino or hydroxyl; V'' is hydrogen or amino or hydroxyl; W is amino or a carboxylic acid or sulfonic acid group; and W'' is hydrogen or amino, or a carboxylic acid or sulfonic acid group; as well as with the alkali metal salts thereof.
Claim 3
Dependent Claim
46 words
Diagnostic agent as claimed in claim 1 for use in the determination of peroxidase or peroxidatively active substances which agent comprises (1) a member selected from the group consisting of hydrogen peroxide and substances forming hydrogen peroxide and (2) a chromogen as defined in claim 1.
Claim 4
Dependent Claim
69 words
Diagnostic agent as claimed in claim 4 additionally containing a modifier compound having the formula: wherein Ar is a benzene or naphthalene nucleus; V is amino or hydroxyl; V'' is hydrogen or amino or hydroxyl; W is amino or a carboxylic acid or sulfonic acid group; and W'' is hydrogen or amino, or a carboxylic acid or sulfonic acid group; as well as with the alkali metal salts thereof.
Claim 5
Dependent Claim
19 words
Diagnostic agent as claimed in claim 1 in the form of a test paper impregnated with said diagnostic agent.
Claim 6
Dependent Claim
19 words
Diagnostic agent as claimed in claim 1 in the form of a test film impregnated with said diagnostic agent.
Claim 7
Dependent Claim
14 words
Diagnostic agent as claimed in claim 1 in the form of a solution thereof.
Claim 8
Dependent Claim
69 words
Diagnostic agent as claimed in claim 1 additionally containing a modifier compound having the formula: wherein Ar is a benzene or naphthalene nucleus; V is amino or hydroxyl; V'' is hydrogen or amino or hydroxyl; W is amino or a carboxylic acid or sulfonic acid group; and W'' is hydrogen or amino, or a carboxylic acid or sulfonic acid group; as well as with the alkali metal salts thereof.
Claim 9
Dependent Claim
14 words
Diagnostic agent as claimed in claim 9 wherein said modifier compound is o-amino-phenol-p-sulfonic acid.
Claim 10
Dependent Claim
14 words
Diagnostic agent as claimed in claim 9 wherein said modifier compound is p-amino-salicylic acid.
Claim 11
Dependent Claim
70 words
Process for the analytical determination of (a) hydroperoxide and a substance which reacts with the liberation of hydroperoxide or (b) peroxidase and a peroxidatively active substance which comprises contacting a liquid containing the substance of interest with a reagent comprising a diagnostic agent according to claim 9, and producing a color with respect to said liquid as visual evidence of the presence of said substance of interest in said liquid.
Claim 12
Dependent Claim
13 words
Diagnostic agent as claimed in claim 1 wherein said chromogen (I) is 1-(1-methyl-benzo(f)quinoline-2-one)-2-(3-ethyl-benzthiazol-2-one)-azine.
Claim 13
Dependent Claim
13 words
Diagnostic agent as claimed in claim 1 wherein said chromogen (I) is 1-(1-methyl-benzo-(f)quinoline-2-one)-2-(1-ethyl-quinoline-2-one)-azine.
Claim 14
Dependent Claim
13 words
Diagnostic agent as claimed in claim 1 wherein said chromogen (I) is 1-(1-methyl-benzo-(f)quinoline-2-one)-2-(3-ethyl-benzoxazol-2-one)-azine.
Claim 15
Dependent Claim
14 words
Diagnostic agent as claimed in claim 1 wherein said chromogen (I) is 1-(1-methyl-benzo(f)quinoline-2-one)-2-(1,3-diethyl-benzimidazol-2-one) -azine.
Claim 16
Dependent Claim
14 words
Diagnostic agent as claimed in claim 1 wherein said chromogen (I) is 2,2''-azino-di-(1-methyl-benzo(f)quinoline) .
Claim 17
Dependent Claim
70 words
Process for the analytical determination of (a) hydroperoxide and a substance which reacts with the liberation of hydroperoxide or (b) peroxidase and a peroXidatively active substance which comprises contacting a liquid containing the substance of interest with a reagent comprising a diagnostic agent according to claim 1 and producing a color with respect to said liquid as visual evidence of the presence of said substance of interest in said liquid.
References Cited (Backward Citations)
US3183173A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1974-12-13 | 1975-06-14 | 1975-12-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1978-12-13 | 1979-06-14 | 1979-12-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1982-12-13 | 1983-06-14 | 1983-12-14 | $7700.00 | Window Closed / Lapsed |