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1-(disubstituted phenyl or benzyl)-1h-indazol-3-yloxyacetic acid

Assignee: Bayer Corp
•
Filing: 1968-04-17
•
Granted: 1971-12-07
•
Expires: 1988-04-17
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Abstract

Abstract Chemical compounds in which the hydroxyl hydrogen atom of a 1(disubstituted phenyl or benzyl)-1H-indazol-3-ol is replaced by a carboxymethyl moiety to yield 1-(disubstituted phenyl or benzyl)1H-indazol-3-yloxyacetic acids are described. The compounds can be prepared by forming the alkali metal salt of the indazol-3-o1 and effecting a Williamson Ether Synthesis reaction with a carboxymethyl halide. The compounds possess anti-inflammatory activity as demonstrated by the Limb Volume Test procedure.

Inventors

  • 👤 Laszlo Ambrus

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 15:45
CPC Classifications
C; C07; C07D; C07D231/00; C07D231/54; C07D231/56; C07C; C07C247/00

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 9 words
A compound of claim 1 wherein n is 0.
Claim 2
Dependent Claim 9 words
A compound of claim 1 wherein n is 1.
Claim 3
Dependent Claim 7 words
A compound of claim 1, (1-(3,5-bis(trifluoromethy)phenyl)-1H-indazol-3-yloxy)-acetic acid.
Claim 4
Dependent Claim 7 words
A compound of claim 1, (1-(2-chloro-5-trifluoromethylphenyl)-1H-indazol-3-yloxy)-acetic acid.
Claim 5
Dependent Claim 7 words
A compound of claim 1, (1-(3,5-bis-trifluoromethyl)-benzyl)-1H-indazol-3-yloxy)-acetic acid.

References Cited (Backward Citations)

GB1054833A Cited
GB1088973A Cited
US3470194A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1974-12-06 1975-06-07 1975-12-07 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1978-12-06 1979-06-07 1979-12-07 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1982-12-06 1983-06-07 1983-12-07 $7700.00 Window Closed / Lapsed

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