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US3622677A Expired / Lapsed US ⏱️ 0.0 years remaining

Compressed tablets containing compacted starch as binder-disintegrant ingredient

Assignee: Primary Products Ingredients Americas LLC
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Filing: 1969-07-07
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Granted: 1971-11-23
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Expires: 1989-07-07
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Abstract

Abstract A directly compressed tablet containing as a binder-disintegrant ingredient, a partially cold-water soluble, cold-water swelling starch material derived from compacted granular starch, e.g. compacted native corn starch. The compacted granular starch is a superficially dry, free-flowing powder in which the starch is in the form of a mixture of birefringent granules and nonbirefringent fragments of granules, in which some aggregates of granules and fragments are present. The use of the starch binder-disintegrant ingredient allows active ingredients, e.g. pharmaceuticals, to be tabletted by direct compression.

Inventors

  • 👤 Rolland W P Short
  • 👤 Frank Verbanac

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-29 23:49
CPC Classifications
A; A61; A61J; A61J3/00; A61J3/10; A61K; A61K9/00; A61K9/20; A61K9/2004; A61K9/2022; A61K9/205; A61K9/2059

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 16 words
The compressed tablet according to claim 1 wherein said active ingredient is a pharmaceutically active compound.
Claim 2
Dependent Claim 16 words
The compressed tablet according to claim 1 wherein said active ingredient is a nonpharmaceutically active compound.
Claim 3
Dependent Claim 28 words
The compressed tablet according to claim 1 wherein said compacted starch powder constitutes at least about 50 percent of the total weight amount of binder in said tablet.
Claim 4
Dependent Claim 34 words
The compressed tablet according to claim 1 wherein the amount of said active ingredient in said tablet is in the range of from about 5 percent to about 90 percent dry substance weight basis.
Claim 5
Dependent Claim 81 words
The compressed tablet according to claim 1 wherein said compacted starch powder constitutes at least about 50 percent of the total weight amount of binder in said tablet, has a cold-water solubility in the range of from about 6 to about 20 percent, dry substance weight basis, and a swelling power in the range of from about 3.5 to about 10, and contains, on a total weight basis, from about 45 to about 75 percent of material which is -270 mesh.
Claim 6
Dependent Claim 18 words
The compressed tablet according to claim 6 wherein said compacted starch is a compacted granular cornstarch raw material.
Claim 7
Dependent Claim 55 words
The compressed tablet according to claim 7 wherein said granular cornstarch raw material is bleached native cornstarch and said compacted starch powder has a cold-water solubility in the range of from about 6 to about 15 percent, dry substance weight basis, and a swelling power in the range of from about 5 to about 8.

References Cited (Backward Citations)

US3034911A Cited
US3101299A Cited
US3424842A Cited
US3453368A Cited
US3490742A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1974-11-22 1975-05-24 1975-11-23 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1978-11-22 1979-05-24 1979-11-23 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1982-11-22 1983-05-24 1983-11-23 $7700.00 Window Closed / Lapsed

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