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Method for the biochemical isolation of 1-menthol

Assignee: Takasago International Corp
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Filing: 1969-11-21
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Granted: 1971-11-16
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Expires: 1989-11-21
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Abstract

Abstract Method for the biochemical isolation of 1-menthol. Specifically, an improved method for the optical resolution of racemic menthol utilizing an enzyme, carboxylic ester hydrolase, which is produced by micro-organism belonging to the class of Candida, Saccharomyces, Hansenula, Rhodotorula, Torulopsis, Schizosaccharomyces, Pichia, Sporobolomyces, Debaryomyces, Nadsonia, Trichosporon, Brettanomyces, and Cryptococcus. The 1-menthol may be utilized in perfumes, medicines, etc.

Inventors

  • 👤 Tatsuo Moroe
  • 👤 Satohiko Hattori
  • 👤 Akira Komatsu
  • 👤 Yuzo Yamaguchi

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 20:46
CPC Classifications
A; A47; A47B; A47B95/00; C; C07; C07C; C07C35/00; C07C35/02; C07C35/08; C07C35/12; Y; Y10; Y10S; Y10S435/00; Y10S435/8215; Y10S435/911; Y10S435/921; Y10S435/93; Y10S435/938; Y10S435/94; Y10S435/944

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 14 words
A process as in claim 1, wherein said organic carboxylic acid is acetic acid.
Claim 2
Dependent Claim 22 words
A process as in claim 1, wherein said hydrolyzation is conducted at a temperature of from about 25* to about 45* C.
Claim 3
Dependent Claim 27 words
A process as in claim 1, wherein the amount of enzyme utilized is from about 0.1 to 0.5 percent, by weight, based on the enzyme reaction mixture.
Claim 4
Dependent Claim 32 words
A process as in claim 1, wherein the amount of organic carboxylic ester is in the range of from about 2 to about 10 percent by weight, based on the reaction mixture.
Claim 5
Dependent Claim 23 words
A process as in claim 1, wherein said enzyme is utilized in the form of actively growing micro-organism cells from the defined class.
Claim 6
Dependent Claim 22 words
A process as in claim 1, wherein said enzyme is utilized in the form of a cell-free extract produced from said microorganisms

References Cited (Backward Citations)

US3256156A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1974-11-15 1975-05-17 1975-11-16 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1978-11-15 1979-05-17 1979-11-16 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1982-11-15 1983-05-17 1983-11-16 $7700.00 Window Closed / Lapsed

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