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Devices for testing biological liquids

Assignee: Merck Sharp & Dohme LLC
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Filing: 1968-02-15
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Granted: 1971-09-21
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Expires: 1988-02-15
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Abstract

Abstract Testing devices for biological liquids comprise liquid permeable membranes of uniform chemical composition having a solid diagnostic reagent composition incorporated in at least a portion thereof and having at least one surface portion impenetrable by particles of the order of size of red blood corpuscles. The membranes may be of substantially uniform porosity throughout or they may have a thin skin portion of low effective porosity and a thicker body portion having pores of substantially large effective diameters.

Inventors

  • 👤 Ellery W Stone

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 13:13
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/52; G01N33/521; G01N33/523; B; B01; B01D; B01D61/00; B01D61/38; C; C12; C12Q; C12Q1/00; C12Q1/54; Y; Y10; Y10T; Y10T436/00; Y10T436/14; Y10T436/142222; Y10T436/143333; Y10T436/144444; Y10T436/145555; Y10T436/146666; Y10T436/25; Y10T436/25375; Y10T436/255

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 28 words
A testing device as defined in claim 1 wherein said one surface of the membrane has substantially no surface roughness larger than the size of red blood corpuscles.
Claim 2
Dependent Claim 27 words
A testing device as defined in claim 1 wherein said one surface of the membrane is impenetrable by particles of the order of size of hemoglobin molecules.
Claim 3
Dependent Claim 36 words
A testing device as defined in claim 1 wherein said one surface of the membrane is penetrable by particles not exceeding about 20,000 in molecular weight and impenetrable by particles exceeding about 50,000 in molecular weight.
Claim 4
Dependent Claim 33 words
A testing device as defined in claim 1 wherein a portion of the membrane other than said one surface is penetrable by particles substantially larger than particles capable of penetrating said one surface.
Claim 5
Dependent Claim 28 words
A testing device as defined in claim 1 wherein at least the portion of the membrane other than said one surface includes therein a solid diagnostic reagent composition.
Claim 6
Dependent Claim 32 words
A testing device as defined in claim 1 wherein the diagnostic reagent composition is responsive by a color change to the presence of glucose in biological liquids in contact with the membrane.

References Cited (Backward Citations)

CA659059A Cited
US3092465A Cited
US3298789A Cited
US3418083A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1974-09-20 1975-03-22 1975-09-21 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1978-09-20 1979-03-22 1979-09-21 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1982-09-20 1983-03-22 1983-09-21 $7700.00 Window Closed / Lapsed

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