Patent US3528126A successfully refreshed from Google Patents.
Patent US3607075A successfully refreshed from Google Patents.
US3607075A
Expired / Lapsed
US
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Instrument and method for analyzing complex substances
Assignee: McDonnell Douglas Corp
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Filing: 1968-08-09
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Granted: 1971-09-21
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Expires: 1988-08-09
Abstract
Abstract A chromatographic apparatus including a chromatographic column through which a fluid carrier medium flows. A complex mixture is introduced into the carrier gas medium prior to the column and is resolved into individual compounds which elute at separate times with the continuing passage of the carrier medium. These compounds are introduced separately into a pyrolyzer which reduces them to pyrolytic fragments. The carrier medium with the pyrolytic fragments in it is introduced into another chromatographic column and eluted therefrom at separate times by the continuing flow of the carrier medium. These fragments are detected and cause a chromatogram unique to the compound to be traced. Once a compound has been eluted from the first column, the flow of carrier medium through that column is halted and that column is isolated from the pyrolyzer and second column so that other compounds will not elute and interfere with the pyrolytic fragments from the prior compounds.
Inventors
- 👤 Clarence J Wolf
- 👤 John Q Walker
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 10:58
CPC Classifications
G; G01; G01N; G01N30/00; G01N30/02; G01N30/26; G01N30/38; G01N30/46; G01N30/461; G01N30/84; G01N2030/8405; Y; Y10; Y10T; Y10T436/00; Y10T436/11; Y10T436/117497
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
41 words
A method according to claim 1 wherein the flow of carrier gas is diverted around the first chromatographic column until all of the pyrolytic fragments from the previously eluted component from the first column have eluted from the second chromatographic column.
Claim 2
Dependent Claim
39 words
A method according to claim 1 and further characterized by dividing the flow of the carrier gas before the components in it are pyrolyzed, and analyzing the carrier gas for the presence of eluted components in the carrier gas.
Claim 3
Dependent Claim
36 words
A method according to claim 3 and further characterized by dividing the flow of carrier gas emerging from the second chromatographic column, and analyzing the carrier gas divided out for the presence of eluted pyrolytic fragments.
Claim 4
Independent Claim
307 words
An apparatus for analyzing complex mixtures, said apparatus comprising a source of pressurized carrier gas, a first flow line connected to the source of carrier gas, means connected with the first flow line for introducing the complex mixture into the carrier medium flowing in the first flow line, a first chromatographic column connected at its one end to the first flow line for receiving the flow of carrier gas as well as the complex mixture in that carrier gas whereby the complex mixture will be resolved into components which elute at different times from the first chromatographic column as the carrier gas flows through the first column, a second flow line connected to the opposite end of the first chromatographic column, a valve in the second flow line and further connected with the source of carrier gas upstream from the first column for diverting the carrier gas around and causing it to bypass the first chromatographic column whereby the flow of carrier gas through the first column may be interrupted after the elution of each component from the first column so that intervals between the elution of components is extended, a pyrolyzer connected to the second flow line for receiving the carrier gas having the eluted components therein and for heating the eluted components sufficiently while they are still in the carrier gas to reduce them to pyrolytiC products, the valve preventing the individual components eluted from the first chromatographic column from overrunning each other in and beyond the pyrolyzer so that the individual eluted components are heated separately, and a second chromatographic column connected to the pyrolyzer for receiving the flow of carrier gas and pyrolytic products discharged from the pyrolyzer whereby the pyrolytic products of each component from the first column will elute at different intervals from the second column and can thereafter be analyzed.
Claim 5
Dependent Claim
26 words
An apparatus according to claim 5 wherein means are connected with the second flow line for ascertaining when a component elutes from the first chromatographic column.
Claim 6
Dependent Claim
23 words
An apparatus according to claim 6 and further characterized by means for detecting the individual pyrolytic products eluted from the second chromatographic column.
Claim 7
Dependent Claim
53 words
An apparatus according to claim 6 wherein the means for ascertaining the elution of a component from the first column comprises a flow divider in the second flow line and detecting means for sensing the presence of an eluted component in the carrier gas divided from the main flow at the flow divider.
Claim 8
Dependent Claim
15 words
An apparatus according to claim 8 wherein the detecting means is a flame ionization detector.
Claim 9
Dependent Claim
42 words
An apparatus according to claim 6 and further characterized by relief means for reducing the pressure of the carrier gas within the first chromatographic column when the valve is adjusted to direct the carrier gas around and thereby bypass the first column.
Claim 10
Dependent Claim
57 words
An apparatus according to claim 10 wherein the means for detecting pyrolytic products eluted from the second column comprises a flow divider for dividing the flow of carrier gas after it discharges from the second column and a flame ionization detector for sensing the presence of pyrolytic products in the flow divided out by the flow divider.
References Cited (Backward Citations)
US3141323A
Cited
US3403978A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1974-09-20 | 1975-03-22 | 1975-09-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1978-09-20 | 1979-03-22 | 1979-09-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1982-09-20 | 1983-03-22 | 1983-09-21 | $7700.00 | Window Closed / Lapsed |