Patent US3598805A successfully refreshed from Google Patents.
US3598805A
Expired / Lapsed
US
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Erythromycin ester derivatives
Assignee: Abbott Laboratories
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Filing: 1970-02-26
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Granted: 1971-08-10
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Expires: 1990-02-26
Abstract
Abstract THE 4''-HYDROXYVERYTHROMYCIN A AND B DERIVATIVES TOGETHER WITH ITS ACID-ADDITION SALTS HAVE BEEN FOUND TO HAVE ANTIBIOTIC ACTIVITY. THE COMPOUND HAS BEEN MADE BY OXIDATION OF ERYTHROMYCIN A OR B TO THE N OXIDE, FOLLOWED BY PYROLYSIS TO 3-(DEDIMETHYLAMINO)-$2''4''-ERYTHROMYCIN. THE UNSATURATE IS THEN EPOXIDIZED AND 3''-(DEDIMETHYLAMINO) - 3''-AZIDO-4''-HYDROXYVERYTHROMYCIN FORMED BY OPENING THE EPOXY RING WITH AN AZIDE. THE AZIDE IS THEN REDUCED TO 3''-(DEDIMETHYLAMINO)-3''-AMINO-4''-HYDROXYVERYTHROMYCIN, WHICH IS FURTHER REDUCED IN THE PRESENCE OF FORMALDEHYDE TO 4''-HYDROXYERYTHROMYCIN.
Inventors
- 👤 Peter Hadley Jones
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 16:06
CPC Classifications
C; C07; C07H; C07H17/00; C07H17/04; C07H17/08
Claims Analysis
Total Claims: 0
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References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1974-08-09 | 1975-02-08 | 1975-08-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1978-08-09 | 1979-02-08 | 1979-08-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1982-08-09 | 1983-02-08 | 1983-08-10 | $7700.00 | Window Closed / Lapsed |