Patent US3553225A successfully refreshed from Google Patents.
US3553225A
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US
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1-(1-hydroxy-1-phenyl-4-aminobutyl)-and 1-(1-phenyl-4-aminobutenyl)-ada-mantane derivatives
Assignee: Smith Kline & French Laboratories Ltd
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Filing: 1968-03-25
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Granted: 1971-01-05
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Expires: 1988-03-25
Abstract
Abstract 1-(1-HYDROXY-1-PHENYL-4-AMINOBUTYL)- AND 1-(1-PHENYL4 - AMINOBUTENYL)-ADAMATANE DERIVATIVES IN WHICH THE PHENYL RING MAY BE CHLORO, TRIFLUOROMETHYL, METHYL, METHOXY OR METHYLTHIO SUBSTITUTED AND THE AMINO GROUP MAY BE DILOWERALKYLAMINO, N-PIPERIDINYL, N-PYRROLIDINYL, N''-LOWER ALKYKL-N-PIPERAZINYL OR N-MORPHOLINYL ARE USEFUL AS TRANQUILIZERS. THE COMPOUNDS ARE GENERALLY PREPARED BY REACTION OF AN APPROPRIATE 1-ADAMANTYL PHENYL KETONE WITH AN AMINOPROPYL MAGNESIUM HALIDE TO GIVE THE HYDROXYBUTANES FOLLOWED BY ACID DEHYDRATION TO FURNISH THE BUTENE DERIVATIVES.
Inventors
- 👤 Carl Kaiser
- 👤 Charles L Zirkle
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 09:53
CPC Classifications
C; C07; C07D; C07D295/00; C07D295/04; C07D295/08; C07D295/084; C07D295/092
Claims Analysis
Total Claims: 0
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References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1974-01-04 | 1974-07-06 | 1975-01-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1978-01-04 | 1978-07-06 | 1979-01-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1982-01-04 | 1982-07-06 | 1983-01-05 | $7700.00 | Window Closed / Lapsed |