US3300385A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method for measuring osmotic fragility of red blood corpuscles
Assignee: Yeda Research and Development Co Ltd
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Filing: 1962-04-27
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Granted: 1967-01-24
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Expires: 1982-04-27
Abstract
No abstract record available.
Inventors
- 👤 Danon David
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 02:07
CPC Classifications
G; G01; G01N; G01N13/00; G01N13/04
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
116 words
A METHOD FOR AUTOMATICALLY MEASURING THE OSMOTIC FRAGILITY OF RED BLOOD CELLS, WHICH COMPRISES: DISPOSING A FIRST ISOTONIC SALT-CONTAINING SOLUTION HAVING A SUSPENSION OF RED BLOOD CELLS, AND A SECOND HYPOTONIC SOLUTION, IN A TEST CELL ON OPPOSITE SIDES OF A DIALYSIS MEMBRANE; ALLOWING A PORTION OF THE SALT-CONTAINING SOLUTION TO DIFFUSE THROUGH SAID MEMBRANE BY OSMOSIS TO RENDER SAID FIRST SOLUTION HYPOTONIC WITH RESPECT TO SAID SUSPENSION OF RED BLOOD CELLS AND EFFECT HEMOLYSIS FROM SAID CELLS TO SAID FIRST, NOW HYPOTONIC, SOLUTION; AND CONCURRENTLY, AT PREDETERMINED INTERVALS PHOTOELECTRICALLY MEASURING AND RECORDING THE LIGHT TRANSMISSIVITY OF SAID SUSPENSION OF RED BLOOD CELLS TO DETERMINE THE OSMOTIC FRAGILITY OF SAID CELLS AS A FUNCTION OF TIME.
Claim 2
Independent Claim
116 words
A METHOD FOR AUTOMATICALLY MEASURING THE OSMOTIC FRAGILITY OF RED BLOOD CELLS, WHICH COMPRISES: DISPOSING A FIRST ISOTONIC SALT-CONTAINING SOLUTION HAVING A SUSPENSION OF RED BLOOD CELLS, AND A SECOND HYPOTONIC SOLUTION, IN A TEST CELL ON OPPOSITE SIDES OF A DIALYSIS MEMBRANE; ALLOWING A PORTION OF THE SALT-CONTAINING SOLUTION TO DIFFUSE THROUGH SAID MEMBRANE BY OSMOSIS TO RENDER SAID FIRST SOLUTION HYPOTONIC WITH RESPECT TO SAID SUSPENSION OF RED BLOOD CELLS AND EFFECT HEMOLYSIS FROM SAID CELLS TO SAID FIRST, NOW HYPOTONIC, SOLUTION; AND CONCURRENTLY, AT PREDETERMINED INTERVALS PHOTOELECTRICALLY MEASURING AND RECORDING THE LIGHT TRANSMISSIVITY OF SAID SUSPENSION OF RED BLOOD CELLS TO DETERMINE THE OSMOTIC FRAGILITY OF SAID CELLS AS A FUNCTION OF TIME.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1970-01-23 | 1970-07-25 | 1971-01-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1974-01-23 | 1974-07-25 | 1975-01-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1978-01-23 | 1978-07-25 | 1979-01-24 | $7700.00 | Window Closed / Lapsed |