Shaped medicaments and process for their manufacture

Claim 1

A SUPPOSITORY FOR RECTAL AND VAGINAL APPLICATION COMPRISING AN EFFECTIVE AMOUNT OF A SOLID THERAPEUTICALLY ACTIVE COMPONENT THEREFOR AND ABOUT 8 PERCENT TO ABOUT 97 PERCENT BY WEIGHT OF A SOLID LYOPHILIC, NON-TOXIC CARRIER COMPRISING MATERIALS SELECTED FROM THE GROUP CONSISTING OF GELATINE, MUCILAGE, POLYETHYLENE OXIDES, HAVING AN AVERAGE MOLECULAR WEIGHT AT LEAST ABOUT 6000, STARCH, DEXTRIN, GLUCOSE, LACTOSE, SACCHAROSE, A HIGHER ALIPHATIC ESTER OF POLYOXYETHYLENE SORBITAN, SODIUM DISILICATE, SILICIC ACID AND WATER-SOLUBLE DERIVATIVES OF ALUMINUM OXIDE AND ALUMINUM HYDROXIDE, SAID SUPPOSITORY HAVING BEEN OBTAINED BY DRYING UNDER VACUUM IN THE FROZEN AND SHAPED STATE THE MIXTURE OF THE THERAPEUTICALLY ACTIVE COMPONENT, THE SOLID LYOPHILIC, NON-TOXIC CARRIER AND AN AQUEOUS DILUENT, WHICH DILUENT CONTAINS SAID SOLID INGREDIENTS IN A PROPOTION OF ABOUT 6 TO ABOUT 60 PERCENT BY WEIGHT, SAID SUPPOSITORY RETAINING SUBSTANTIALLY THE FORM OF THE FROZEN STATE.