New n-benzyl peptides and a process of making same

Claim 1

IN A PROCESS OF PRODUCING POLYPEPTIDE COMPOUNDS, THE STEPS COMPRISING ADDING, PORTION BY PORTION, THE HYDROCHLORIDE OF AN ACID CHLORIDE OF AN N-BENZYLATED AMINO ACID TO A SOLUTION, IN DIOXANE, OF AN AMINO COMPOUND SELECTED FROM THE GROUP CONSISTING OF AN AMINO ACID AND A PEPTIDE, THE CARBOXYL GROUP OF SAID AMINO COMPOUND BEING CONVERTED INTO AN ESTER GROUP, KEEPING THE TEMPERATURE DURING ADDITION OF SAID N-BENZYLATED COMPOUND AT A TEMPERATURE BETWEEN ABOUT 0*C. AND ABOUT 5*C. AND PH VALUE OF THE MIXTURE AT A PH BETWEEN ABOUT 7.0 AND ABOUT 8.0 BY THE ADDITION OF ALKALI HYDROXIDE SOLUTION, REMOVING THE DIOXANE BY DISTILLATION IN A VACUUM, EXTRACTING THE REACTION MIXTURE BY MEANS OF CHLOROFORM, AGITATING THE RESULTING CHLOROFORM SOLUTION WITH HYDROCHLORIC ACID, EVAPORATING THE ACID-TREATED CHLORFORM SOLUTION TO DRYNESS, AND SAPONIFYING THE HYDROCHLORIDE OF THE ESTER OF THE RESULTING N-BENZYLATED PEPTIDE BY BOILING UNDER REFLUX ITS SOLUTION IN METHANOLIC ALKALI HYDROXIDE SOLUTION