Patent US2934473A successfully refreshed from Google Patents.
US2934473A
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Bovine rhinotracheitis vaccine and methods of production
Assignee: ALLIED LAB Inc
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Filing: 1956-08-27
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Granted: 1960-04-26
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Expires: 1976-08-27
Abstract
No abstract record available.
Inventors
- 👤 Charles J York
- 👤 Anton J F Schwarz
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 22:03
CPC Classifications
A; A61; A61K; A61K39/00; A61K39/12; A61K39/245; A61K39/265; A61K2039/51; A61K2039/525; A61K2039/5254; A61K2039/55; A61K2039/552; C; C12; C12N; C12N2710/00; C12N2710/00011; C12N2710/16011; C12N2710/16711; C12N2710/16734; Y; Y10; Y10S; Y10S424/00; Y10S424/813
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
120 words
A METHOD OF MODIFYING INFECTIOUS BOVINE RHINOTRACHEITIS VIRUS WHICH COMPRISES INOCULATING A NUTRIENT FLUID CONTAINING BOVINE KIDNEY TISSUE CULTURE CELLS WITH A VIRULENT INFECTIOUS BOVINE RHINOTRACHEITIS VIRUS, SAID INOCULATING VIRUS HAVING BEEN OBTAINED IN A RELATIVELY HIGH CONCENTRATION BY PROPAGATION IN VITRO IN BOVINE TISSUE CULTURES, INCUBATING SAID NUTRIENT FLUID TISSUE CULTURE MEDIUM FOR A PERIOD OF ONE TO TWO DAYS, THEREAFTER SEPARATING AN INOCULUM OF SAID VIRUS AND PASSING THE VIRUS THROUGH OTHER SUCH BOVINE TISSUE CULTURES FOR A TOTAL OF AT LEAST 40 ONE- TO TWO-DAY SERIAL PASSAGES WHEREBY THE VIRUS IS SO MODIFIED THAT IT WILL NO LONGER DEVELOP PATHOLOGICAL SYMPTOMS WHEN INJECTED INTO A NORMAL BOVINE BUT WILL GIVE RISE TO THE PRODUCTION OF PROTECTIVE ANTIBODIES.
Claim 2
Independent Claim
120 words
A METHOD OF MODIFYING INFECTIOUS BOVINE RHINOTRACHEITIS VIRUS WHICH COMPRISES INOCULATING A NUTRIENT FLUID CONTAINING BOVINE KIDNEY TISSUE CULTURE CELLS WITH A VIRULENT INFECTIOUS BOVINE RHINOTRACHEITIS VIRUS, SAID INOCULATING VIRUS HAVING BEEN OBTAINED IN A RELATIVELY HIGH CONCENTRATION BY PROPAGATION IN VITRO IN BOVINE TISSUE CULTURES, INCUBATING SAID NUTRIENT FLUID TISSUE CULTURE MEDIUM FOR A PERIOD OF ONE TO TWO DAYS, THEREAFTER SEPARATING AN INOCULUM OF SAID VIRUS AND PASSING THE VIRUS THROUGH OTHER SUCH BOVINE TISSUE CULTURES FOR A TOTAL OF AT LEAST 40 ONE- TO TWO-DAY SERIAL PASSAGES WHEREBY THE VIRUS IS SO MODIFIED THAT IT WILL NO LONGER DEVELOP PATHOLOGICAL SYMPTOMS WHEN INJECTED INTO A NORMAL BOVINE BUT WILL GIVE RISE TO THE PRODUCTION OF PROTECTIVE ANTIBODIES.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1963-04-26 | 1963-10-26 | 1964-04-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1967-04-26 | 1967-10-26 | 1968-04-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1971-04-26 | 1971-10-26 | 1972-04-26 | $7700.00 | Window Closed / Lapsed |