Patent US5048203A successfully refreshed from Google Patents.
Patent US2885412A successfully refreshed from Google Patents.
US2885412A
Expired / Lapsed
US
⏱️ 0.0 years remaining
9alpha-fluoro-delta 1-3, 20-diketo-11, 21-bis-oxy-genated-17-hydroxy-allopregnenes and processes for preparing them
Assignee: Merck and Co Inc
•
Filing: 1955-05-26
•
Granted: 1959-05-05
•
Expires: 1975-05-26
Abstract
No abstract record available.
Inventors
- 👤 Ralph F Hirschmann
- 👤 Miller Richard
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 15:43
CPC Classifications
C; C07; C07J; C07J5/00; C07J75/00
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
135 words
THE PROCESS WHICH COMPRISES REACTING 9A-FLUORO3,11,20 - TRIKETO - 17A - HYDROXY -21 - LOWER ALKANOYLOXY-ALLOPREGANE WITH ONE MOLECULAR EQUIVALENT OF BROMINE TO FORM THE 2-BORMINATED DERIVATIVE, REACTING THIS COMPOUND WITH SEMICARBAZIDE TO FORM 9A-FLUORO-$1-3,11, 20 - TRIKETO - 17A - HYDROXY - 21 - LOWER ALKANOYLOXYALLOPREGENE 3-SEMICARBAZONE, REACTING THIS 3-SEMICARBAZONE WITH AN AQUEOUS SOLUTION OF ACETIC ACID IN THE PRESENCE OF PYRUVIC ACID THEREBY FORMING 9A-FLUORO-$3,11, 20 - TRIKETO - 17A,21 - DIHYDROXY - ALLOPREGNENE 21 - ACYLATE, AND REACTING SAID 9A - FLUORO - $1 - 3,11,20 - TRIKETO17A,21 - DIHYDROXY - ALLOPREGENE 21 - ACYLATE WITH A METHANOLIC SOLUTION OF POTASSIUM HYDROXIDE TO PRODUCE 9A - FLUORO - $1 - 3,11,20 - TRIKETO - 17A,21 - DIHYDROXYALLOPREGENE. 3. 9A - FLUORO - $1 - 3,11,20 - TRIKETO - 17A - HYDROXY21-LOWER ALKANOYLOXY-ALLOPREGENNE.
Claim 2
Dependent Claim
135 words
THE PROCESS WHICH COMPRISES REACTING 9A-FLUORO3,11,20 - TRIKETO - 17A - HYDROXY -21 - LOWER ALKANOYLOXY-ALLOPREGANE WITH ONE MOLECULAR EQUIVALENT OF BROMINE TO FORM THE 2-BORMINATED DERIVATIVE, REACTING THIS COMPOUND WITH SEMICARBAZIDE TO FORM 9A-FLUORO-$1-3,11, 20 - TRIKETO - 17A - HYDROXY - 21 - LOWER ALKANOYLOXYALLOPREGENE 3-SEMICARBAZONE, REACTING THIS 3-SEMICARBAZONE WITH AN AQUEOUS SOLUTION OF ACETIC ACID IN THE PRESENCE OF PYRUVIC ACID THEREBY FORMING 9A-FLUORO-$3,11, 20 - TRIKETO - 17A,21 - DIHYDROXY - ALLOPREGNENE 21 - ACYLATE, AND REACTING SAID 9A - FLUORO - $1 - 3,11,20 - TRIKETO17A,21 - DIHYDROXY - ALLOPREGENE 21 - ACYLATE WITH A METHANOLIC SOLUTION OF POTASSIUM HYDROXIDE TO PRODUCE 9A - FLUORO - $1 - 3,11,20 - TRIKETO - 17A,21 - DIHYDROXYALLOPREGENE. 3. 9A - FLUORO - $1 - 3,11,20 - TRIKETO - 17A - HYDROXY21-LOWER ALKANOYLOXY-ALLOPREGENNE.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1962-05-04 | 1962-11-03 | 1963-05-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1966-05-04 | 1966-11-03 | 1967-05-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1970-05-04 | 1970-11-03 | 1971-05-05 | $7700.00 | Window Closed / Lapsed |