Patent US2881163A successfully refreshed from Google Patents.
US2881163A
Expired / Lapsed
US
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Process of preparing salts
Assignee: Abbott Laboratories
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Filing: 1953-11-16
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Granted: 1959-04-07
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Expires: 1973-11-16
Abstract
No abstract record available.
Inventors
- 👤 Otto F Walasek
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 06:03
CPC Classifications
C; C07; C07H; C07H17/00; C07H17/04; C07H17/08
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
181 words
IN A PROCESS OF REVOCERING ERYTHROMYCIN FATTY ACID SALT RELATIVELY FREE OF IMPURITIES, THE STEPS COMPRISING: ADMIXING AN AQUEOUS SOLUTION OF A CRUDE ERYTHROMYCIN SALT WITH A WATER-MISCIBLE ORGANIC SOLVENT IN WHICH THE ERYTHROMYCIN IS RELATIVELY SOLUBLE WHILE MAINTAINING THE PH AT ABOUT 8.5 AND THE TEMPERATURE BETWEEN ABOUT 35* C. AND 45* C., ADDING AN INORGANIC SALT WHICH IS RELATIVELY SOLUBLE IN WATER TO CAUSE A SEPARATION OF THE ORGANIC SOLVENT FROM THE WATER PHASE CONTAINING THE SAID INORGANIC SALT, ADJUSTING THE PH OF THE SAID SOLUTION TO BETWEEN ABOUT PH 9.5 AND UU WHILE MAINTAINING THE TEMPERATURE OF THE SAID SOLUTION TO BETWEEN ABOUT 35* C. AND 45* C., WHEREBY THE ORGANIC SOLVENT SOLUTION CONTAINING THE ERYTHROMYCIN ACTIVITY SEPARATES FROM THE WATER PHASE CONTAINING THE SAID SALT; SEPARATING THE SAID ORGANIC SOLVENT SOLUTION FROM THE SAID WATER PHASE; ADDING TO THE SAID ORGANIC SOLVENT PHASE A COMPOUND CONTAINING AN ACTIVE FATTY ACID GROUP WHICH FORMS AN ERYTHROMYCIN FATTY ACID ADDITION SALT; AND CRYSTALLIZING THE SAID ERYTHROMYCIN FATTY ACID ADDITION SALT FROM THE SAID ORGANIC SOLVENT RELATIVELY FRE OF IMPURITIES.
Claim 2
Dependent Claim
181 words
IN A PROCESS OF REVOCERING ERYTHROMYCIN FATTY ACID SALT RELATIVELY FREE OF IMPURITIES, THE STEPS COMPRISING: ADMIXING AN AQUEOUS SOLUTION OF A CRUDE ERYTHROMYCIN SALT WITH A WATER-MISCIBLE ORGANIC SOLVENT IN WHICH THE ERYTHROMYCIN IS RELATIVELY SOLUBLE WHILE MAINTAINING THE PH AT ABOUT 8.5 AND THE TEMPERATURE BETWEEN ABOUT 35* C. AND 45* C., ADDING AN INORGANIC SALT WHICH IS RELATIVELY SOLUBLE IN WATER TO CAUSE A SEPARATION OF THE ORGANIC SOLVENT FROM THE WATER PHASE CONTAINING THE SAID INORGANIC SALT, ADJUSTING THE PH OF THE SAID SOLUTION TO BETWEEN ABOUT PH 9.5 AND UU WHILE MAINTAINING THE TEMPERATURE OF THE SAID SOLUTION TO BETWEEN ABOUT 35* C. AND 45* C., WHEREBY THE ORGANIC SOLVENT SOLUTION CONTAINING THE ERYTHROMYCIN ACTIVITY SEPARATES FROM THE WATER PHASE CONTAINING THE SAID SALT; SEPARATING THE SAID ORGANIC SOLVENT SOLUTION FROM THE SAID WATER PHASE; ADDING TO THE SAID ORGANIC SOLVENT PHASE A COMPOUND CONTAINING AN ACTIVE FATTY ACID GROUP WHICH FORMS AN ERYTHROMYCIN FATTY ACID ADDITION SALT; AND CRYSTALLIZING THE SAID ERYTHROMYCIN FATTY ACID ADDITION SALT FROM THE SAID ORGANIC SOLVENT RELATIVELY FRE OF IMPURITIES.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1962-04-06 | 1962-10-06 | 1963-04-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1966-04-06 | 1966-10-06 | 1967-04-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1970-04-06 | 1970-10-06 | 1971-04-07 | $7700.00 | Window Closed / Lapsed |